Anti-NUP205 monoclonal antibody

Pre-made anti-NUP205 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to NUP205/NUP205 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1288-Ab-1/ GM-Tg-hg-IP1288-Ab-2Anti-Human NUP205 monoclonal antibodyHuman
GM-Tg-rg-IP1288-Ab-1/ GM-Tg-rg-IP1288-Ab-2Anti-Rat NUP205 monoclonal antibodyRat
GM-Tg-mg-IP1288-Ab-1/ GM-Tg-mg-IP1288-Ab-2Anti-Mouse NUP205 monoclonal antibodyMouse
GM-Tg-cynog-IP1288-Ab-1/ GM-Tg-cynog-IP1288-Ab-2Anti-Cynomolgus/ Rhesus macaque NUP205 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1288-Ab-1/ GM-Tg-felg-IP1288-Ab-2Anti-Feline NUP205 monoclonal antibodyFeline
GM-Tg-cang-IP1288-Ab-1/ GM-Tg-cang-IP1288-Ab-2Anti-Canine NUP205 monoclonal antibodyCanine
GM-Tg-bovg-IP1288-Ab-1/ GM-Tg-bovg-IP1288-Ab-2Anti-Bovine NUP205 monoclonal antibodyBovine
GM-Tg-equg-IP1288-Ab-1/ GM-Tg-equg-IP1288-Ab-2Anti-Equine NUP205 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1288-Ab-1/ GM-Tg-hg-IP1288-Ab-2; GM-Tg-rg-IP1288-Ab-1/ GM-Tg-rg-IP1288-Ab-2;
GM-Tg-mg-IP1288-Ab-1/ GM-Tg-mg-IP1288-Ab-2; GM-Tg-cynog-IP1288-Ab-1/ GM-Tg-cynog-IP1288-Ab-2;
GM-Tg-felg-IP1288-Ab-1/ GM-Tg-felg-IP1288-Ab-2; GM-Tg-cang-IP1288-Ab-1/ GM-Tg-cang-IP1288-Ab-2;
GM-Tg-bovg-IP1288-Ab-1/ GM-Tg-bovg-IP1288-Ab-2; GM-Tg-equg-IP1288-Ab-1/ GM-Tg-equg-IP1288-Ab-2
Products NameAnti-NUP205 monoclonal antibody
Formatmab
Target NameNUP205
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-NUP205 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1288-Ag-1Recombinant multi-species NU205/ NUP205/ C7orf14 protein


    Target information

    Target IDGM-IP1288
    Target NameNUP205
    Gene ID23165,70699,362335,708216,475506,101097383,520924,100064995
    Gene Symbol and Synonyms3830404O05Rik,C7orf14,mKIAA0225,NPHS13,NUP205
    Uniprot AccessionQ92621
    Uniprot Entry NameNU205_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000155561
    Target ClassificationN/A

    The target: NUP205, gene name: NUP205, also named as C7orf14, NPHS13. This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with steroid-resistant nephrotic syndrome. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.