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Anti-PAPOLG monoclonal antibody
Pre-made anti-PAPOLG monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PAPOLG/PAPOLG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1322-Ab-1/ GM-Tg-hg-IP1322-Ab-2 | Anti-Human PAPOLG monoclonal antibody | Human |
| GM-Tg-rg-IP1322-Ab-1/ GM-Tg-rg-IP1322-Ab-2 | Anti-Rat PAPOLG monoclonal antibody | Rat |
| GM-Tg-mg-IP1322-Ab-1/ GM-Tg-mg-IP1322-Ab-2 | Anti-Mouse PAPOLG monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1322-Ab-1/ GM-Tg-cynog-IP1322-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PAPOLG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1322-Ab-1/ GM-Tg-felg-IP1322-Ab-2 | Anti-Feline PAPOLG monoclonal antibody | Feline |
| GM-Tg-cang-IP1322-Ab-1/ GM-Tg-cang-IP1322-Ab-2 | Anti-Canine PAPOLG monoclonal antibody | Canine |
| GM-Tg-bovg-IP1322-Ab-1/ GM-Tg-bovg-IP1322-Ab-2 | Anti-Bovine PAPOLG monoclonal antibody | Bovine |
| GM-Tg-equg-IP1322-Ab-1/ GM-Tg-equg-IP1322-Ab-2 | Anti-Equine PAPOLG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1322-Ab-1/ GM-Tg-hg-IP1322-Ab-2; GM-Tg-rg-IP1322-Ab-1/ GM-Tg-rg-IP1322-Ab-2; GM-Tg-mg-IP1322-Ab-1/ GM-Tg-mg-IP1322-Ab-2; GM-Tg-cynog-IP1322-Ab-1/ GM-Tg-cynog-IP1322-Ab-2; GM-Tg-felg-IP1322-Ab-1/ GM-Tg-felg-IP1322-Ab-2; GM-Tg-cang-IP1322-Ab-1/ GM-Tg-cang-IP1322-Ab-2; GM-Tg-bovg-IP1322-Ab-1/ GM-Tg-bovg-IP1322-Ab-2; GM-Tg-equg-IP1322-Ab-1/ GM-Tg-equg-IP1322-Ab-2 |
| Products Name | Anti-PAPOLG monoclonal antibody |
| Format | mab |
| Target Name | PAPOLG |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PAPOLG monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1322-Ag-1 | Recombinant multi-species PAPOG/ PAPOLG protein |
Target information
| Target ID | GM-IP1322 |
| Target Name | PAPOLG |
| Gene ID | 64895,216578,305586,717781,481382,101082998,529071,100052114 |
| Gene Symbol and Synonyms | 9630006B20Rik,PAPOLG |
| Uniprot Accession | Q9BWT3 |
| Uniprot Entry Name | PAPOG_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000115421 |
| Target Classification | N/A |
The target: PAPOLG, gene name: PAPOLG, also named as . This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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