Anti-PCNX1 monoclonal antibody

Pre-made anti-PCNX1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PCNX1/PCNX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1359-Ab-1/ GM-Tg-hg-IP1359-Ab-2Anti-Human PCNX1 monoclonal antibodyHuman
GM-Tg-rg-IP1359-Ab-1/ GM-Tg-rg-IP1359-Ab-2Anti-Rat PCNX1 monoclonal antibodyRat
GM-Tg-mg-IP1359-Ab-1/ GM-Tg-mg-IP1359-Ab-2Anti-Mouse PCNX1 monoclonal antibodyMouse
GM-Tg-cynog-IP1359-Ab-1/ GM-Tg-cynog-IP1359-Ab-2Anti-Cynomolgus/ Rhesus macaque PCNX1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1359-Ab-1/ GM-Tg-felg-IP1359-Ab-2Anti-Feline PCNX1 monoclonal antibodyFeline
GM-Tg-cang-IP1359-Ab-1/ GM-Tg-cang-IP1359-Ab-2Anti-Canine PCNX1 monoclonal antibodyCanine
GM-Tg-bovg-IP1359-Ab-1/ GM-Tg-bovg-IP1359-Ab-2Anti-Bovine PCNX1 monoclonal antibodyBovine
GM-Tg-equg-IP1359-Ab-1/ GM-Tg-equg-IP1359-Ab-2Anti-Equine PCNX1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1359-Ab-1/ GM-Tg-hg-IP1359-Ab-2; GM-Tg-rg-IP1359-Ab-1/ GM-Tg-rg-IP1359-Ab-2;
GM-Tg-mg-IP1359-Ab-1/ GM-Tg-mg-IP1359-Ab-2; GM-Tg-cynog-IP1359-Ab-1/ GM-Tg-cynog-IP1359-Ab-2;
GM-Tg-felg-IP1359-Ab-1/ GM-Tg-felg-IP1359-Ab-2; GM-Tg-cang-IP1359-Ab-1/ GM-Tg-cang-IP1359-Ab-2;
GM-Tg-bovg-IP1359-Ab-1/ GM-Tg-bovg-IP1359-Ab-2; GM-Tg-equg-IP1359-Ab-1/ GM-Tg-equg-IP1359-Ab-2
Products NameAnti-PCNX1 monoclonal antibody
Formatmab
Target NamePCNX1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PCNX1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1359-Ag-1Recombinant multi-species PCX1/ PCNX1/ PCNX protein


    Target information

    Target IDGM-IP1359
    Target NamePCNX1
    Gene ID22990,54604,314288,694094,480378,105260647,514244,100054565
    Gene Symbol and Synonyms2900024E21Rik,3526401J03Rik,PCNX,PCNX1,PCNXL1,pecanex
    Uniprot AccessionQ96RV3,E9PSU6
    Uniprot Entry NamePCX1_HUMAN,PCX1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000100731
    Target ClassificationN/A

    The target: PCNX1, gene name: PCNX1, also named as PCNX, PCNXL1, pecanex. This gene encodes an evolutionarily conserved transmembrane protein similar to the pecanex protein in Drosophila. The fly protein is a component of the Notch signaling pathway, which functions in several developmental processes. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.