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Anti-PGAP3 monoclonal antibody
Pre-made anti-PGAP3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PGAP3/PGAP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1380-Ab-1/ GM-Tg-hg-IP1380-Ab-2 | Anti-Human PGAP3 monoclonal antibody | Human |
| GM-Tg-rg-IP1380-Ab-1/ GM-Tg-rg-IP1380-Ab-2 | Anti-Rat PGAP3 monoclonal antibody | Rat |
| GM-Tg-mg-IP1380-Ab-1/ GM-Tg-mg-IP1380-Ab-2 | Anti-Mouse PGAP3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1380-Ab-1/ GM-Tg-cynog-IP1380-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PGAP3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1380-Ab-1/ GM-Tg-felg-IP1380-Ab-2 | Anti-Feline PGAP3 monoclonal antibody | Feline |
| GM-Tg-cang-IP1380-Ab-1/ GM-Tg-cang-IP1380-Ab-2 | Anti-Canine PGAP3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1380-Ab-1/ GM-Tg-bovg-IP1380-Ab-2 | Anti-Bovine PGAP3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1380-Ab-1/ GM-Tg-equg-IP1380-Ab-2 | Anti-Equine PGAP3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1380-Ab-1/ GM-Tg-hg-IP1380-Ab-2; GM-Tg-rg-IP1380-Ab-1/ GM-Tg-rg-IP1380-Ab-2; GM-Tg-mg-IP1380-Ab-1/ GM-Tg-mg-IP1380-Ab-2; GM-Tg-cynog-IP1380-Ab-1/ GM-Tg-cynog-IP1380-Ab-2; GM-Tg-felg-IP1380-Ab-1/ GM-Tg-felg-IP1380-Ab-2; GM-Tg-cang-IP1380-Ab-1/ GM-Tg-cang-IP1380-Ab-2; GM-Tg-bovg-IP1380-Ab-1/ GM-Tg-bovg-IP1380-Ab-2; GM-Tg-equg-IP1380-Ab-1/ GM-Tg-equg-IP1380-Ab-2 |
| Products Name | Anti-PGAP3 monoclonal antibody |
| Format | mab |
| Target Name | PGAP3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PGAP3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1380-Ag-1 | Recombinant multi-species PGAP3/ AGLA546/ CAB2 protein |
Target information
| Target ID | GM-IP1380 |
| Target Name | PGAP3 |
| Gene ID | 93210,320655,688174,697699,491022,101091739,513258,100068111 |
| Gene Symbol and Synonyms | AGLA546,CAB2,D430035D22Rik,hCOS16,PERLD1,PGAP3,PP1498 |
| Uniprot Accession | Q96FM1,A7YWP2 |
| Uniprot Entry Name | PGAP3_HUMAN,PGAP3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000161395 |
| Target Classification | N/A |
The target: PGAP3, gene name: PGAP3, also named as AGLA546, CAB2, PERLD1, PP1498, hCOS16. This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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