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Anti-PIGF monoclonal antibody
Pre-made anti-PIGF monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PIGF/PIGF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1389-Ab-1/ GM-Tg-hg-IP1389-Ab-2 | Anti-Human PIGF monoclonal antibody | Human |
| GM-Tg-rg-IP1389-Ab-1/ GM-Tg-rg-IP1389-Ab-2 | Anti-Rat PIGF monoclonal antibody | Rat |
| GM-Tg-mg-IP1389-Ab-1/ GM-Tg-mg-IP1389-Ab-2 | Anti-Mouse PIGF monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1389-Ab-1/ GM-Tg-cynog-IP1389-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIGF monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1389-Ab-1/ GM-Tg-felg-IP1389-Ab-2 | Anti-Feline PIGF monoclonal antibody | Feline |
| GM-Tg-cang-IP1389-Ab-1/ GM-Tg-cang-IP1389-Ab-2 | Anti-Canine PIGF monoclonal antibody | Canine |
| GM-Tg-bovg-IP1389-Ab-1/ GM-Tg-bovg-IP1389-Ab-2 | Anti-Bovine PIGF monoclonal antibody | Bovine |
| GM-Tg-equg-IP1389-Ab-1/ GM-Tg-equg-IP1389-Ab-2 | Anti-Equine PIGF monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1389-Ab-1/ GM-Tg-hg-IP1389-Ab-2; GM-Tg-rg-IP1389-Ab-1/ GM-Tg-rg-IP1389-Ab-2; GM-Tg-mg-IP1389-Ab-1/ GM-Tg-mg-IP1389-Ab-2; GM-Tg-cynog-IP1389-Ab-1/ GM-Tg-cynog-IP1389-Ab-2; GM-Tg-felg-IP1389-Ab-1/ GM-Tg-felg-IP1389-Ab-2; GM-Tg-cang-IP1389-Ab-1/ GM-Tg-cang-IP1389-Ab-2; GM-Tg-bovg-IP1389-Ab-1/ GM-Tg-bovg-IP1389-Ab-2; GM-Tg-equg-IP1389-Ab-1/ GM-Tg-equg-IP1389-Ab-2 |
| Products Name | Anti-PIGF monoclonal antibody |
| Format | mab |
| Target Name | PIGF |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PIGF monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1389-Ag-1 | Recombinant multi-species PIGF protein |
| ORF Viral Vector | vGMLP000052 | human PIGF Lentivirus particle |
| ORF Viral Vector | pGMLP000052 | human PIGF Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001115 | mouse Pigf Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001115 | mouse Pigf Lentivirus particle |
Target information
| Target ID | GM-IP1389 |
| Target Name | PIGF |
| Gene ID | 5281,18701,681086,714844,474580,101101456,768015,100053298 |
| Gene Symbol and Synonyms | OORS,PIGF,RHOQ |
| Uniprot Accession | Q07326 |
| Uniprot Entry Name | PIGF_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000151665 |
| Target Classification | N/A |
The target: PIGF, gene name: PIGF, also named as . This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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