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Anti-PIGM monoclonal antibody
Pre-made anti-PIGM monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PIGM/PIGM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1392-Ab-1/ GM-Tg-hg-IP1392-Ab-2 | Anti-Human PIGM monoclonal antibody | Human |
| GM-Tg-rg-IP1392-Ab-1/ GM-Tg-rg-IP1392-Ab-2 | Anti-Rat PIGM monoclonal antibody | Rat |
| GM-Tg-mg-IP1392-Ab-1/ GM-Tg-mg-IP1392-Ab-2 | Anti-Mouse PIGM monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1392-Ab-1/ GM-Tg-cynog-IP1392-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIGM monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1392-Ab-1/ GM-Tg-felg-IP1392-Ab-2 | Anti-Feline PIGM monoclonal antibody | Feline |
| GM-Tg-cang-IP1392-Ab-1/ GM-Tg-cang-IP1392-Ab-2 | Anti-Canine PIGM monoclonal antibody | Canine |
| GM-Tg-bovg-IP1392-Ab-1/ GM-Tg-bovg-IP1392-Ab-2 | Anti-Bovine PIGM monoclonal antibody | Bovine |
| GM-Tg-equg-IP1392-Ab-1/ GM-Tg-equg-IP1392-Ab-2 | Anti-Equine PIGM monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1392-Ab-1/ GM-Tg-hg-IP1392-Ab-2; GM-Tg-rg-IP1392-Ab-1/ GM-Tg-rg-IP1392-Ab-2; GM-Tg-mg-IP1392-Ab-1/ GM-Tg-mg-IP1392-Ab-2; GM-Tg-cynog-IP1392-Ab-1/ GM-Tg-cynog-IP1392-Ab-2; GM-Tg-felg-IP1392-Ab-1/ GM-Tg-felg-IP1392-Ab-2; GM-Tg-cang-IP1392-Ab-1/ GM-Tg-cang-IP1392-Ab-2; GM-Tg-bovg-IP1392-Ab-1/ GM-Tg-bovg-IP1392-Ab-2; GM-Tg-equg-IP1392-Ab-1/ GM-Tg-equg-IP1392-Ab-2 |
| Products Name | Anti-PIGM monoclonal antibody |
| Format | mab |
| Target Name | PIGM |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PIGM monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1392-Ag-1 | Recombinant multi-species PIGM/ GPI-MT-I protein |
| ORF Viral Vector | vGMLP002523 | human PIGM Lentivirus particle |
| ORF Viral Vector | pGMLP002523 | human PIGM Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002139 | mouse Pigm Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002139 | mouse Pigm Lentivirus particle |
Target information
| Target ID | GM-IP1392 |
| Target Name | PIGM |
| Gene ID | 93183,67556,79112,719582,119868076,101097541,509680,100058075 |
| Gene Symbol and Synonyms | 4933437L05Rik,C920011G20Rik,GPI-MT-I,LOC119868076,PIGM |
| Uniprot Accession | Q9H3S5,Q9EQY6,Q5EA10 |
| Uniprot Entry Name | PIGM_HUMAN,PIGM_RAT,PIGM_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143315 |
| Target Classification | N/A |
The target: PIGM, gene name: PIGM, also named as GPI-MT-I. This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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