Anti-PKDREJ monoclonal antibody

Pre-made anti-PKDREJ monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PKDREJ/PKDREJ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1405-Ab-1/ GM-Tg-hg-IP1405-Ab-2Anti-Human PKDREJ monoclonal antibodyHuman
GM-Tg-rg-IP1405-Ab-1/ GM-Tg-rg-IP1405-Ab-2Anti-Rat PKDREJ monoclonal antibodyRat
GM-Tg-mg-IP1405-Ab-1/ GM-Tg-mg-IP1405-Ab-2Anti-Mouse PKDREJ monoclonal antibodyMouse
GM-Tg-cynog-IP1405-Ab-1/ GM-Tg-cynog-IP1405-Ab-2Anti-Cynomolgus/ Rhesus macaque PKDREJ monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1405-Ab-1/ GM-Tg-felg-IP1405-Ab-2Anti-Feline PKDREJ monoclonal antibodyFeline
GM-Tg-cang-IP1405-Ab-1/ GM-Tg-cang-IP1405-Ab-2Anti-Canine PKDREJ monoclonal antibodyCanine
GM-Tg-bovg-IP1405-Ab-1/ GM-Tg-bovg-IP1405-Ab-2Anti-Bovine PKDREJ monoclonal antibodyBovine
GM-Tg-equg-IP1405-Ab-1/ GM-Tg-equg-IP1405-Ab-2Anti-Equine PKDREJ monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1405-Ab-1/ GM-Tg-hg-IP1405-Ab-2; GM-Tg-rg-IP1405-Ab-1/ GM-Tg-rg-IP1405-Ab-2;
GM-Tg-mg-IP1405-Ab-1/ GM-Tg-mg-IP1405-Ab-2; GM-Tg-cynog-IP1405-Ab-1/ GM-Tg-cynog-IP1405-Ab-2;
GM-Tg-felg-IP1405-Ab-1/ GM-Tg-felg-IP1405-Ab-2; GM-Tg-cang-IP1405-Ab-1/ GM-Tg-cang-IP1405-Ab-2;
GM-Tg-bovg-IP1405-Ab-1/ GM-Tg-bovg-IP1405-Ab-2; GM-Tg-equg-IP1405-Ab-1/ GM-Tg-equg-IP1405-Ab-2
Products NameAnti-PKDREJ monoclonal antibody
Formatmab
Target NamePKDREJ
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PKDREJ monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1405-Ag-1Recombinant multi-species PKDRE/ PKDREJ protein


    Target information

    Target IDGM-IP1405
    Target NamePKDREJ
    Gene ID10343,18766,300124,714030,474466,101096820,102151050
    Gene Symbol and SynonymsPKDREJ
    Uniprot AccessionQ9NTG1
    Uniprot Entry NamePKDRE_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000130943
    Target ClassificationN/A

    The target: PKDREJ, gene name: PKDREJ, also named as . This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.