Anti-PLD4 monoclonal antibody

Pre-made anti-PLD4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PLD4/PLD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1409-Ab-1/ GM-Tg-hg-IP1409-Ab-2Anti-Human PLD4 monoclonal antibodyHuman
GM-Tg-rg-IP1409-Ab-1/ GM-Tg-rg-IP1409-Ab-2Anti-Rat PLD4 monoclonal antibodyRat
GM-Tg-mg-IP1409-Ab-1/ GM-Tg-mg-IP1409-Ab-2Anti-Mouse PLD4 monoclonal antibodyMouse
GM-Tg-cynog-IP1409-Ab-1/ GM-Tg-cynog-IP1409-Ab-2Anti-Cynomolgus/ Rhesus macaque PLD4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1409-Ab-1/ GM-Tg-felg-IP1409-Ab-2Anti-Feline PLD4 monoclonal antibodyFeline
GM-Tg-cang-IP1409-Ab-1/ GM-Tg-cang-IP1409-Ab-2Anti-Canine PLD4 monoclonal antibodyCanine
GM-Tg-bovg-IP1409-Ab-1/ GM-Tg-bovg-IP1409-Ab-2Anti-Bovine PLD4 monoclonal antibodyBovine
GM-Tg-equg-IP1409-Ab-1/ GM-Tg-equg-IP1409-Ab-2Anti-Equine PLD4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1409-Ab-1/ GM-Tg-hg-IP1409-Ab-2; GM-Tg-rg-IP1409-Ab-1/ GM-Tg-rg-IP1409-Ab-2;
GM-Tg-mg-IP1409-Ab-1/ GM-Tg-mg-IP1409-Ab-2; GM-Tg-cynog-IP1409-Ab-1/ GM-Tg-cynog-IP1409-Ab-2;
GM-Tg-felg-IP1409-Ab-1/ GM-Tg-felg-IP1409-Ab-2; GM-Tg-cang-IP1409-Ab-1/ GM-Tg-cang-IP1409-Ab-2;
GM-Tg-bovg-IP1409-Ab-1/ GM-Tg-bovg-IP1409-Ab-2; GM-Tg-equg-IP1409-Ab-1/ GM-Tg-equg-IP1409-Ab-2
Products NameAnti-PLD4 monoclonal antibody
Formatmab
Target NamePLD4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PLD4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1409-Ag-1Recombinant multi-species PLD4/ C14orf175 protein


    Target information

    Target IDGM-IP1409
    Target NamePLD4
    Gene ID122618,104759,362792,707527,612697,101088418,789315,100146639
    Gene Symbol and SynonymsC14orf175,PLD4,thss
    Uniprot AccessionQ96BZ4
    Uniprot Entry NamePLD4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000166428
    Target ClassificationN/A

    The target: PLD4, gene name: PLD4, also named as C14orf175. Predicted to enable single-stranded DNA 5'-3' exodeoxyribonuclease activity. Predicted to be involved in hematopoietic progenitor cell differentiation; phagocytosis; and regulation of cytokine production involved in inflammatory response. Predicted to be located in early endosome and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including endoplasmic reticulum; phagocytic vesicle; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.