Anti-PNPLA7 monoclonal antibody

Pre-made anti-PNPLA7 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PNPLA7/PNPLA7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1421-Ab-1/ GM-Tg-hg-IP1421-Ab-2Anti-Human PNPLA7 monoclonal antibodyHuman
GM-Tg-rg-IP1421-Ab-1/ GM-Tg-rg-IP1421-Ab-2Anti-Rat PNPLA7 monoclonal antibodyRat
GM-Tg-mg-IP1421-Ab-1/ GM-Tg-mg-IP1421-Ab-2Anti-Mouse PNPLA7 monoclonal antibodyMouse
GM-Tg-cynog-IP1421-Ab-1/ GM-Tg-cynog-IP1421-Ab-2Anti-Cynomolgus/ Rhesus macaque PNPLA7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1421-Ab-1/ GM-Tg-felg-IP1421-Ab-2Anti-Feline PNPLA7 monoclonal antibodyFeline
GM-Tg-cang-IP1421-Ab-1/ GM-Tg-cang-IP1421-Ab-2Anti-Canine PNPLA7 monoclonal antibodyCanine
GM-Tg-bovg-IP1421-Ab-1/ GM-Tg-bovg-IP1421-Ab-2Anti-Bovine PNPLA7 monoclonal antibodyBovine
GM-Tg-equg-IP1421-Ab-1/ GM-Tg-equg-IP1421-Ab-2Anti-Equine PNPLA7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1421-Ab-1/ GM-Tg-hg-IP1421-Ab-2; GM-Tg-rg-IP1421-Ab-1/ GM-Tg-rg-IP1421-Ab-2;
GM-Tg-mg-IP1421-Ab-1/ GM-Tg-mg-IP1421-Ab-2; GM-Tg-cynog-IP1421-Ab-1/ GM-Tg-cynog-IP1421-Ab-2;
GM-Tg-felg-IP1421-Ab-1/ GM-Tg-felg-IP1421-Ab-2; GM-Tg-cang-IP1421-Ab-1/ GM-Tg-cang-IP1421-Ab-2;
GM-Tg-bovg-IP1421-Ab-1/ GM-Tg-bovg-IP1421-Ab-2; GM-Tg-equg-IP1421-Ab-1/ GM-Tg-equg-IP1421-Ab-2
Products NameAnti-PNPLA7 monoclonal antibody
Formatmab
Target NamePNPLA7
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PNPLA7 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1421-Ag-1Recombinant multi-species PLPL7/ PNPLA7/ C9orf111 protein


    Target information

    Target IDGM-IP1421
    Target NamePNPLA7
    Gene ID375775,241274,246246,721508,480663,101086099,536255,100059297
    Gene Symbol and SynonymsC9orf111,E430013P11Rik,Nre,NTE-R1,Nte-related,Ntel,NTEL1,PNPLA7
    Uniprot AccessionQ6ZV29,Q5BK26
    Uniprot Entry NamePLPL7_HUMAN,PLPL7_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000130653
    Target ClassificationN/A

    The target: PNPLA7, gene name: PNPLA7, also named as C9orf111, NTE-R1, NTEL1. Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.