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Anti-POMT1 monoclonal antibody
Pre-made anti-POMT1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to POMT1/POMT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1429-Ab-1/ GM-Tg-hg-IP1429-Ab-2 | Anti-Human POMT1 monoclonal antibody | Human |
| GM-Tg-rg-IP1429-Ab-1/ GM-Tg-rg-IP1429-Ab-2 | Anti-Rat POMT1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1429-Ab-1/ GM-Tg-mg-IP1429-Ab-2 | Anti-Mouse POMT1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1429-Ab-1/ GM-Tg-cynog-IP1429-Ab-2 | Anti-Cynomolgus/ Rhesus macaque POMT1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1429-Ab-1/ GM-Tg-felg-IP1429-Ab-2 | Anti-Feline POMT1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1429-Ab-1/ GM-Tg-cang-IP1429-Ab-2 | Anti-Canine POMT1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1429-Ab-1/ GM-Tg-bovg-IP1429-Ab-2 | Anti-Bovine POMT1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1429-Ab-1/ GM-Tg-equg-IP1429-Ab-2 | Anti-Equine POMT1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1429-Ab-1/ GM-Tg-hg-IP1429-Ab-2; GM-Tg-rg-IP1429-Ab-1/ GM-Tg-rg-IP1429-Ab-2; GM-Tg-mg-IP1429-Ab-1/ GM-Tg-mg-IP1429-Ab-2; GM-Tg-cynog-IP1429-Ab-1/ GM-Tg-cynog-IP1429-Ab-2; GM-Tg-felg-IP1429-Ab-1/ GM-Tg-felg-IP1429-Ab-2; GM-Tg-cang-IP1429-Ab-1/ GM-Tg-cang-IP1429-Ab-2; GM-Tg-bovg-IP1429-Ab-1/ GM-Tg-bovg-IP1429-Ab-2; GM-Tg-equg-IP1429-Ab-1/ GM-Tg-equg-IP1429-Ab-2 |
| Products Name | Anti-POMT1 monoclonal antibody |
| Format | mab |
| Target Name | POMT1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-POMT1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1429-Ag-1 | Recombinant multi-species POMT1/ LGMD2K/ LGMDR11 protein |
| ORF Viral Vector | pGMLP001550 | human POMT1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001550 | human POMT1 Lentivirus particle |
Target information
| Target ID | GM-IP1429 |
| Target Name | POMT1 |
| Gene ID | 10585,99011,84430,722387,608039,101088629,617609,100069575 |
| Gene Symbol and Synonyms | LGMD2K,LGMDR11,MDDGA1,MDDGB1,MDDGC1,POMT1,RT |
| Uniprot Accession | Q9Y6A1,Q99PR0 |
| Uniprot Entry Name | POMT1_HUMAN,POMT1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130714 |
| Target Classification | N/A |
The target: POMT1, gene name: POMT1, also named as LGMD2K, LGMDR11, MDDGA1, MDDGB1, MDDGC1, RT. The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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