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Anti-PPAN monoclonal antibody
Pre-made anti-PPAN monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PPAN/PPAN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1433-Ab-1/ GM-Tg-hg-IP1433-Ab-2 | Anti-Human PPAN monoclonal antibody | Human |
| GM-Tg-rg-IP1433-Ab-1/ GM-Tg-rg-IP1433-Ab-2 | Anti-Rat PPAN monoclonal antibody | Rat |
| GM-Tg-mg-IP1433-Ab-1/ GM-Tg-mg-IP1433-Ab-2 | Anti-Mouse PPAN monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1433-Ab-1/ GM-Tg-cynog-IP1433-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PPAN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1433-Ab-1/ GM-Tg-felg-IP1433-Ab-2 | Anti-Feline PPAN monoclonal antibody | Feline |
| GM-Tg-cang-IP1433-Ab-1/ GM-Tg-cang-IP1433-Ab-2 | Anti-Canine PPAN monoclonal antibody | Canine |
| GM-Tg-bovg-IP1433-Ab-1/ GM-Tg-bovg-IP1433-Ab-2 | Anti-Bovine PPAN monoclonal antibody | Bovine |
| GM-Tg-equg-IP1433-Ab-1/ GM-Tg-equg-IP1433-Ab-2 | Anti-Equine PPAN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1433-Ab-1/ GM-Tg-hg-IP1433-Ab-2; GM-Tg-rg-IP1433-Ab-1/ GM-Tg-rg-IP1433-Ab-2; GM-Tg-mg-IP1433-Ab-1/ GM-Tg-mg-IP1433-Ab-2; GM-Tg-cynog-IP1433-Ab-1/ GM-Tg-cynog-IP1433-Ab-2; GM-Tg-felg-IP1433-Ab-1/ GM-Tg-felg-IP1433-Ab-2; GM-Tg-cang-IP1433-Ab-1/ GM-Tg-cang-IP1433-Ab-2; GM-Tg-bovg-IP1433-Ab-1/ GM-Tg-bovg-IP1433-Ab-2; GM-Tg-equg-IP1433-Ab-1/ GM-Tg-equg-IP1433-Ab-2 |
| Products Name | Anti-PPAN monoclonal antibody |
| Format | mab |
| Target Name | PPAN |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PPAN monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1433-Ag-1 | Recombinant multi-species SSF1/ PPAN/ BXDC3 protein |
Target information
| Target ID | GM-IP1433 |
| Target Name | PPAN |
| Gene ID | 56342,235036 |
| Gene Symbol and Synonyms | A230087P06Rik,BXDC3,PPAN,SSF,SSF-1,SSF1,SSF2 |
| Uniprot Accession | Q9NQ55 |
| Uniprot Entry Name | SSF1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130810 |
| Target Classification | N/A |
The target: PPAN, gene name: PPAN, also named as BXDC3, SSF, SSF-1, SSF1, SSF2. The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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