Anti-PQLC1 monoclonal antibody

Pre-made anti-PQLC1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PQLC1/PQLC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1439-Ab-1/ GM-Tg-hg-IP1439-Ab-2Anti-Human PQLC1 monoclonal antibodyHuman
GM-Tg-rg-IP1439-Ab-1/ GM-Tg-rg-IP1439-Ab-2Anti-Rat PQLC1 monoclonal antibodyRat
GM-Tg-mg-IP1439-Ab-1/ GM-Tg-mg-IP1439-Ab-2Anti-Mouse PQLC1 monoclonal antibodyMouse
GM-Tg-cynog-IP1439-Ab-1/ GM-Tg-cynog-IP1439-Ab-2Anti-Cynomolgus/ Rhesus macaque PQLC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1439-Ab-1/ GM-Tg-felg-IP1439-Ab-2Anti-Feline PQLC1 monoclonal antibodyFeline
GM-Tg-cang-IP1439-Ab-1/ GM-Tg-cang-IP1439-Ab-2Anti-Canine PQLC1 monoclonal antibodyCanine
GM-Tg-bovg-IP1439-Ab-1/ GM-Tg-bovg-IP1439-Ab-2Anti-Bovine PQLC1 monoclonal antibodyBovine
GM-Tg-equg-IP1439-Ab-1/ GM-Tg-equg-IP1439-Ab-2Anti-Equine PQLC1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1439-Ab-1/ GM-Tg-hg-IP1439-Ab-2; GM-Tg-rg-IP1439-Ab-1/ GM-Tg-rg-IP1439-Ab-2;
GM-Tg-mg-IP1439-Ab-1/ GM-Tg-mg-IP1439-Ab-2; GM-Tg-cynog-IP1439-Ab-1/ GM-Tg-cynog-IP1439-Ab-2;
GM-Tg-felg-IP1439-Ab-1/ GM-Tg-felg-IP1439-Ab-2; GM-Tg-cang-IP1439-Ab-1/ GM-Tg-cang-IP1439-Ab-2;
GM-Tg-bovg-IP1439-Ab-1/ GM-Tg-bovg-IP1439-Ab-2; GM-Tg-equg-IP1439-Ab-1/ GM-Tg-equg-IP1439-Ab-2
Products NameAnti-PQLC1 monoclonal antibody
Formatmab
Target NamePQLC1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PQLC1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1439-Ag-1Recombinant multi-species S66A2/ PQLC1/ SLC66A2 protein


    Target information

    Target IDGM-IP1439
    Target NamePQLC1
    Gene ID80148,66943,361352,698716,476157,101097023,533304,100052336
    Gene Symbol and Synonyms2310009N05Rik,4933425L21Rik,5730564E11Rik,PQLC1,SLC66A2
    Uniprot AccessionQ8N2U9,Q5M880,Q0VCC1
    Uniprot Entry NameS66A2_HUMAN,S66A2_RAT,S66A2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000122490
    Target ClassificationN/A

    The target: PQLC1, gene name: PQLC1, also named as SLC66A2. Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be integral component of membrane. Predicted to be active in endosome and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.