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Anti-PRPH2 monoclonal antibody
Pre-made anti-PRPH2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PRPH2/PRPH2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1447-Ab-1/ GM-Tg-hg-IP1447-Ab-2 | Anti-Human PRPH2 monoclonal antibody | Human |
| GM-Tg-rg-IP1447-Ab-1/ GM-Tg-rg-IP1447-Ab-2 | Anti-Rat PRPH2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1447-Ab-1/ GM-Tg-mg-IP1447-Ab-2 | Anti-Mouse PRPH2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1447-Ab-1/ GM-Tg-cynog-IP1447-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRPH2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1447-Ab-1/ GM-Tg-felg-IP1447-Ab-2 | Anti-Feline PRPH2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1447-Ab-1/ GM-Tg-cang-IP1447-Ab-2 | Anti-Canine PRPH2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1447-Ab-1/ GM-Tg-bovg-IP1447-Ab-2 | Anti-Bovine PRPH2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1447-Ab-1/ GM-Tg-equg-IP1447-Ab-2 | Anti-Equine PRPH2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1447-Ab-1/ GM-Tg-hg-IP1447-Ab-2; GM-Tg-rg-IP1447-Ab-1/ GM-Tg-rg-IP1447-Ab-2; GM-Tg-mg-IP1447-Ab-1/ GM-Tg-mg-IP1447-Ab-2; GM-Tg-cynog-IP1447-Ab-1/ GM-Tg-cynog-IP1447-Ab-2; GM-Tg-felg-IP1447-Ab-1/ GM-Tg-felg-IP1447-Ab-2; GM-Tg-cang-IP1447-Ab-1/ GM-Tg-cang-IP1447-Ab-2; GM-Tg-bovg-IP1447-Ab-1/ GM-Tg-bovg-IP1447-Ab-2; GM-Tg-equg-IP1447-Ab-1/ GM-Tg-equg-IP1447-Ab-2 |
| Products Name | Anti-PRPH2 monoclonal antibody |
| Format | mab |
| Target Name | PRPH2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PRPH2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1447-Ag-1 | Recombinant multi-species PRPH2/ AOFMD/ AVMD protein |
Target information
| Target ID | GM-IP1447 |
| Target Name | PRPH2 |
| Gene ID | 5961,19133,25534,696630,403972,727697,280907,100054746 |
| Gene Symbol and Synonyms | AOFMD,AVMD,CACD2,DS,MDBS1,Nmf193,PRPH,PRPH2,Rd-2,rd2,RDS,RP7,RSRDS,TSPAN22 |
| Uniprot Accession | P23942,P17438,P52204,P35906,P17810 |
| Uniprot Entry Name | PRPH2_HUMAN,PRPH2_RAT,PRPH2_FELCA,PRPH2_CANLF,PRPH2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112619 |
| Target Classification | N/A |
The target: PRPH2, gene name: PRPH2, also named as AOFMD, AVMD, CACD2, DS, MDBS1, PRPH, RDS, RP7, TSPAN22, rd2. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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