Anti-PRRT1 monoclonal antibody

Pre-made anti-PRRT1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PRRT1/PRRT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1450-Ab-1/ GM-Tg-hg-IP1450-Ab-2Anti-Human PRRT1 monoclonal antibodyHuman
GM-Tg-rg-IP1450-Ab-1/ GM-Tg-rg-IP1450-Ab-2Anti-Rat PRRT1 monoclonal antibodyRat
GM-Tg-mg-IP1450-Ab-1/ GM-Tg-mg-IP1450-Ab-2Anti-Mouse PRRT1 monoclonal antibodyMouse
GM-Tg-cynog-IP1450-Ab-1/ GM-Tg-cynog-IP1450-Ab-2Anti-Cynomolgus/ Rhesus macaque PRRT1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1450-Ab-1/ GM-Tg-felg-IP1450-Ab-2Anti-Feline PRRT1 monoclonal antibodyFeline
GM-Tg-cang-IP1450-Ab-1/ GM-Tg-cang-IP1450-Ab-2Anti-Canine PRRT1 monoclonal antibodyCanine
GM-Tg-bovg-IP1450-Ab-1/ GM-Tg-bovg-IP1450-Ab-2Anti-Bovine PRRT1 monoclonal antibodyBovine
GM-Tg-equg-IP1450-Ab-1/ GM-Tg-equg-IP1450-Ab-2Anti-Equine PRRT1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1450-Ab-1/ GM-Tg-hg-IP1450-Ab-2; GM-Tg-rg-IP1450-Ab-1/ GM-Tg-rg-IP1450-Ab-2;
GM-Tg-mg-IP1450-Ab-1/ GM-Tg-mg-IP1450-Ab-2; GM-Tg-cynog-IP1450-Ab-1/ GM-Tg-cynog-IP1450-Ab-2;
GM-Tg-felg-IP1450-Ab-1/ GM-Tg-felg-IP1450-Ab-2; GM-Tg-cang-IP1450-Ab-1/ GM-Tg-cang-IP1450-Ab-2;
GM-Tg-bovg-IP1450-Ab-1/ GM-Tg-bovg-IP1450-Ab-2; GM-Tg-equg-IP1450-Ab-1/ GM-Tg-equg-IP1450-Ab-2
Products NameAnti-PRRT1 monoclonal antibody
Formatmab
Target NamePRRT1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PRRT1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1450-Ag-1Recombinant multi-species PRRT1/ C6orf31/ DSPD1 protein


    Target information

    Target IDGM-IP1450
    Target NamePRRT1
    Gene ID80863,260297,406167,717111,607660,101095337,617717,100051413
    Gene Symbol and SynonymsBat-4,Bat4,C6orf31,D17H6S54E,DSPD1,G5b,IFI™D7,NG5,ORF31,PRRT1,SynDIG4
    Uniprot AccessionQ99946,Q6MG82
    Uniprot Entry NamePRRT1_HUMAN,PRRT1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000204314
    Target ClassificationN/A

    The target: PRRT1, gene name: PRRT1, also named as C6orf31, DSPD1, IFI™D7, NG5. Enables identical protein binding activity. Predicted to be involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA receptor activity. Predicted to act upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Predicted to be located in postsynaptic density membrane and synaptic vesicle membrane. Predicted to be active in glutamatergic synapse and membrane. Predicted to be integral component of postsynaptic membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.