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Anti-PTPRH monoclonal antibody
Pre-made anti-PTPRH monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PTPRH/PTPRH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1459-Ab-1/ GM-Tg-hg-IP1459-Ab-2 | Anti-Human PTPRH monoclonal antibody | Human |
| GM-Tg-rg-IP1459-Ab-1/ GM-Tg-rg-IP1459-Ab-2 | Anti-Rat PTPRH monoclonal antibody | Rat |
| GM-Tg-mg-IP1459-Ab-1/ GM-Tg-mg-IP1459-Ab-2 | Anti-Mouse PTPRH monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1459-Ab-1/ GM-Tg-cynog-IP1459-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PTPRH monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1459-Ab-1/ GM-Tg-felg-IP1459-Ab-2 | Anti-Feline PTPRH monoclonal antibody | Feline |
| GM-Tg-cang-IP1459-Ab-1/ GM-Tg-cang-IP1459-Ab-2 | Anti-Canine PTPRH monoclonal antibody | Canine |
| GM-Tg-bovg-IP1459-Ab-1/ GM-Tg-bovg-IP1459-Ab-2 | Anti-Bovine PTPRH monoclonal antibody | Bovine |
| GM-Tg-equg-IP1459-Ab-1/ GM-Tg-equg-IP1459-Ab-2 | Anti-Equine PTPRH monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1459-Ab-1/ GM-Tg-hg-IP1459-Ab-2; GM-Tg-rg-IP1459-Ab-1/ GM-Tg-rg-IP1459-Ab-2; GM-Tg-mg-IP1459-Ab-1/ GM-Tg-mg-IP1459-Ab-2; GM-Tg-cynog-IP1459-Ab-1/ GM-Tg-cynog-IP1459-Ab-2; GM-Tg-felg-IP1459-Ab-1/ GM-Tg-felg-IP1459-Ab-2; GM-Tg-cang-IP1459-Ab-1/ GM-Tg-cang-IP1459-Ab-2; GM-Tg-bovg-IP1459-Ab-1/ GM-Tg-bovg-IP1459-Ab-2; GM-Tg-equg-IP1459-Ab-1/ GM-Tg-equg-IP1459-Ab-2 |
| Products Name | Anti-PTPRH monoclonal antibody |
| Format | mab |
| Target Name | PTPRH |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PTPRH monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1459-Ag-1 | Recombinant multi-species PTPRH/ R-PTP-H/ SAP1 protein |
Target information
| Target ID | GM-IP1459 |
| Target Name | PTPRH |
| Gene ID | 5794,545902,171125,699032,484299,101092313,521868,100055444 |
| Gene Symbol and Synonyms | Bem2,PTPRH,R-PTP-H,sap-1,SAP1 |
| Uniprot Accession | Q9HD43 |
| Uniprot Entry Name | PTPRH_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000080031 |
| Target Classification | N/A |
The target: PTPRH, gene name: PTPRH, also named as R-PTP-H, SAP1. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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