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Anti-PTTG1IP monoclonal antibody
Pre-made anti-PTTG1IP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PTTG1IP/PTTG1IP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1462-Ab-1/ GM-Tg-hg-IP1462-Ab-2 | Anti-Human PTTG1IP monoclonal antibody | Human |
| GM-Tg-rg-IP1462-Ab-1/ GM-Tg-rg-IP1462-Ab-2 | Anti-Rat PTTG1IP monoclonal antibody | Rat |
| GM-Tg-mg-IP1462-Ab-1/ GM-Tg-mg-IP1462-Ab-2 | Anti-Mouse PTTG1IP monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1462-Ab-1/ GM-Tg-cynog-IP1462-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PTTG1IP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1462-Ab-1/ GM-Tg-felg-IP1462-Ab-2 | Anti-Feline PTTG1IP monoclonal antibody | Feline |
| GM-Tg-cang-IP1462-Ab-1/ GM-Tg-cang-IP1462-Ab-2 | Anti-Canine PTTG1IP monoclonal antibody | Canine |
| GM-Tg-bovg-IP1462-Ab-1/ GM-Tg-bovg-IP1462-Ab-2 | Anti-Bovine PTTG1IP monoclonal antibody | Bovine |
| GM-Tg-equg-IP1462-Ab-1/ GM-Tg-equg-IP1462-Ab-2 | Anti-Equine PTTG1IP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1462-Ab-1/ GM-Tg-hg-IP1462-Ab-2; GM-Tg-rg-IP1462-Ab-1/ GM-Tg-rg-IP1462-Ab-2; GM-Tg-mg-IP1462-Ab-1/ GM-Tg-mg-IP1462-Ab-2; GM-Tg-cynog-IP1462-Ab-1/ GM-Tg-cynog-IP1462-Ab-2; GM-Tg-felg-IP1462-Ab-1/ GM-Tg-felg-IP1462-Ab-2; GM-Tg-cang-IP1462-Ab-1/ GM-Tg-cang-IP1462-Ab-2; GM-Tg-bovg-IP1462-Ab-1/ GM-Tg-bovg-IP1462-Ab-2; GM-Tg-equg-IP1462-Ab-1/ GM-Tg-equg-IP1462-Ab-2 |
| Products Name | Anti-PTTG1IP monoclonal antibody |
| Format | mab |
| Target Name | PTTG1IP |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PTTG1IP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1462-Ag-1 | Recombinant multi-species PTTG/ PTTG1IP/ C21orf1 protein |
Target information
| Target ID | GM-IP1462 |
| Target Name | PTTG1IP |
| Gene ID | 754,108705,365548,722061,100856547,101087513,617245 |
| Gene Symbol and Synonyms | 1810010L20Rik,C21orf1,C21orf3,PBF,PTTG1IP,PTTG1IP1 |
| Uniprot Accession | P53801,Q6P767 |
| Uniprot Entry Name | PTTG_HUMAN,PTTG_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000183255 |
| Target Classification | N/A |
The target: PTTG1IP, gene name: PTTG1IP, also named as C21orf1, C21orf3, PBF. This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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