Anti-RANBP17 monoclonal antibody

Pre-made anti-RANBP17 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RANBP17/RANBP17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1471-Ab-1/ GM-Tg-hg-IP1471-Ab-2Anti-Human RANBP17 monoclonal antibodyHuman
GM-Tg-rg-IP1471-Ab-1/ GM-Tg-rg-IP1471-Ab-2Anti-Rat RANBP17 monoclonal antibodyRat
GM-Tg-mg-IP1471-Ab-1/ GM-Tg-mg-IP1471-Ab-2Anti-Mouse RANBP17 monoclonal antibodyMouse
GM-Tg-cynog-IP1471-Ab-1/ GM-Tg-cynog-IP1471-Ab-2Anti-Cynomolgus/ Rhesus macaque RANBP17 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1471-Ab-1/ GM-Tg-felg-IP1471-Ab-2Anti-Feline RANBP17 monoclonal antibodyFeline
GM-Tg-cang-IP1471-Ab-1/ GM-Tg-cang-IP1471-Ab-2Anti-Canine RANBP17 monoclonal antibodyCanine
GM-Tg-bovg-IP1471-Ab-1/ GM-Tg-bovg-IP1471-Ab-2Anti-Bovine RANBP17 monoclonal antibodyBovine
GM-Tg-equg-IP1471-Ab-1/ GM-Tg-equg-IP1471-Ab-2Anti-Equine RANBP17 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1471-Ab-1/ GM-Tg-hg-IP1471-Ab-2; GM-Tg-rg-IP1471-Ab-1/ GM-Tg-rg-IP1471-Ab-2;
GM-Tg-mg-IP1471-Ab-1/ GM-Tg-mg-IP1471-Ab-2; GM-Tg-cynog-IP1471-Ab-1/ GM-Tg-cynog-IP1471-Ab-2;
GM-Tg-felg-IP1471-Ab-1/ GM-Tg-felg-IP1471-Ab-2; GM-Tg-cang-IP1471-Ab-1/ GM-Tg-cang-IP1471-Ab-2;
GM-Tg-bovg-IP1471-Ab-1/ GM-Tg-bovg-IP1471-Ab-2; GM-Tg-equg-IP1471-Ab-1/ GM-Tg-equg-IP1471-Ab-2
Products NameAnti-RANBP17 monoclonal antibody
Formatmab
Target NameRANBP17
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RANBP17 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1471-Ag-1Recombinant multi-species RBP17/ RANBP17 protein


    Target information

    Target IDGM-IP1471
    Target NameRANBP17
    Gene ID64901,66011,303029,701214,479293,101099021,100337114,100070317
    Gene Symbol and SynonymsRANBP17,RGD1562576
    Uniprot AccessionQ9H2T7
    Uniprot Entry NameRBP17_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000204764
    Target ClassificationTumor-associated antigen (TAA)

    The target: RANBP17, gene name: RANBP17, also named as . The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.