Anti-RHBDD2 monoclonal antibody

Pre-made anti-RHBDD2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RHBDD2/RHBDD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1490-Ab-1/ GM-Tg-hg-IP1490-Ab-2Anti-Human RHBDD2 monoclonal antibodyHuman
GM-Tg-rg-IP1490-Ab-1/ GM-Tg-rg-IP1490-Ab-2Anti-Rat RHBDD2 monoclonal antibodyRat
GM-Tg-mg-IP1490-Ab-1/ GM-Tg-mg-IP1490-Ab-2Anti-Mouse RHBDD2 monoclonal antibodyMouse
GM-Tg-cynog-IP1490-Ab-1/ GM-Tg-cynog-IP1490-Ab-2Anti-Cynomolgus/ Rhesus macaque RHBDD2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1490-Ab-1/ GM-Tg-felg-IP1490-Ab-2Anti-Feline RHBDD2 monoclonal antibodyFeline
GM-Tg-cang-IP1490-Ab-1/ GM-Tg-cang-IP1490-Ab-2Anti-Canine RHBDD2 monoclonal antibodyCanine
GM-Tg-bovg-IP1490-Ab-1/ GM-Tg-bovg-IP1490-Ab-2Anti-Bovine RHBDD2 monoclonal antibodyBovine
GM-Tg-equg-IP1490-Ab-1/ GM-Tg-equg-IP1490-Ab-2Anti-Equine RHBDD2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1490-Ab-1/ GM-Tg-hg-IP1490-Ab-2; GM-Tg-rg-IP1490-Ab-1/ GM-Tg-rg-IP1490-Ab-2;
GM-Tg-mg-IP1490-Ab-1/ GM-Tg-mg-IP1490-Ab-2; GM-Tg-cynog-IP1490-Ab-1/ GM-Tg-cynog-IP1490-Ab-2;
GM-Tg-felg-IP1490-Ab-1/ GM-Tg-felg-IP1490-Ab-2; GM-Tg-cang-IP1490-Ab-1/ GM-Tg-cang-IP1490-Ab-2;
GM-Tg-bovg-IP1490-Ab-1/ GM-Tg-bovg-IP1490-Ab-2; GM-Tg-equg-IP1490-Ab-1/ GM-Tg-equg-IP1490-Ab-2
Products NameAnti-RHBDD2 monoclonal antibody
Formatmab
Target NameRHBDD2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RHBDD2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1490-Ag-1Recombinant multi-species RHBD2/ RHBDD2/ NPD007 protein


    Target information

    Target IDGM-IP1490
    Target NameRHBDD2
    Gene ID57414,215160,360793,720005,489815,101086025,540447,100061144
    Gene Symbol and Synonyms0610011L13Rik,NPD007,RHBDD2,RHBDL7,Usmg1
    Uniprot AccessionQ6NTF9
    Uniprot Entry NameRHBD2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000005486
    Target ClassificationN/A

    The target: RHBDD2, gene name: RHBDD2, also named as NPD007, RHBDL7. The protein encoded by this gene is a member of the rhomboid family of membrane-bound proteases and is overexpressed in some breast cancers. Members of this family are involved in intramembrane proteolysis. In mouse, the orthologous protein associates with the Golgi body. [provided by RefSeq, Sep 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.