Anti-RHOT2 monoclonal antibody

Pre-made anti-RHOT2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RHOT2/RHOT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1496-Ab-1/ GM-Tg-hg-IP1496-Ab-2Anti-Human RHOT2 monoclonal antibodyHuman
GM-Tg-rg-IP1496-Ab-1/ GM-Tg-rg-IP1496-Ab-2Anti-Rat RHOT2 monoclonal antibodyRat
GM-Tg-mg-IP1496-Ab-1/ GM-Tg-mg-IP1496-Ab-2Anti-Mouse RHOT2 monoclonal antibodyMouse
GM-Tg-cynog-IP1496-Ab-1/ GM-Tg-cynog-IP1496-Ab-2Anti-Cynomolgus/ Rhesus macaque RHOT2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1496-Ab-1/ GM-Tg-felg-IP1496-Ab-2Anti-Feline RHOT2 monoclonal antibodyFeline
GM-Tg-cang-IP1496-Ab-1/ GM-Tg-cang-IP1496-Ab-2Anti-Canine RHOT2 monoclonal antibodyCanine
GM-Tg-bovg-IP1496-Ab-1/ GM-Tg-bovg-IP1496-Ab-2Anti-Bovine RHOT2 monoclonal antibodyBovine
GM-Tg-equg-IP1496-Ab-1/ GM-Tg-equg-IP1496-Ab-2Anti-Equine RHOT2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1496-Ab-1/ GM-Tg-hg-IP1496-Ab-2; GM-Tg-rg-IP1496-Ab-1/ GM-Tg-rg-IP1496-Ab-2;
GM-Tg-mg-IP1496-Ab-1/ GM-Tg-mg-IP1496-Ab-2; GM-Tg-cynog-IP1496-Ab-1/ GM-Tg-cynog-IP1496-Ab-2;
GM-Tg-felg-IP1496-Ab-1/ GM-Tg-felg-IP1496-Ab-2; GM-Tg-cang-IP1496-Ab-1/ GM-Tg-cang-IP1496-Ab-2;
GM-Tg-bovg-IP1496-Ab-1/ GM-Tg-bovg-IP1496-Ab-2; GM-Tg-equg-IP1496-Ab-1/ GM-Tg-equg-IP1496-Ab-2
Products NameAnti-RHOT2 monoclonal antibody
Formatmab
Target NameRHOT2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RHOT2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1496-Ag-1Recombinant multi-species MIRO2/ RHOT2/ ARHT2 protein


    Target information

    Target IDGM-IP1496
    Target NameRHOT2
    Gene ID89941,214952,287156,722352,479893,101093322,352959,100066937
    Gene Symbol and SynonymsARHT2,C16orf39,MIRO-2,MIRO2,RASL,RHOT2
    Uniprot AccessionQ8IXI1,Q7TSA0,Q5E9M9
    Uniprot Entry NameMIRO2_HUMAN,MIRO2_RAT,MIRO2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000140983
    Target ClassificationN/A

    The target: RHOT2, gene name: RHOT2, also named as ARHT2, C16orf39, MIRO-2, MIRO2, RASL. This gene encodes a member of the Rho family of GTPases. The encoded protein is localized to the outer mitochondrial membrane and plays a role in mitochondrial trafficking and fusion-fission dynamics. [provided by RefSeq, Nov 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.