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Anti-RNF130 monoclonal antibody
Pre-made anti-RNF130 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RNF130/RNF130 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1505-Ab-1/ GM-Tg-hg-IP1505-Ab-2 | Anti-Human RNF130 monoclonal antibody | Human |
| GM-Tg-rg-IP1505-Ab-1/ GM-Tg-rg-IP1505-Ab-2 | Anti-Rat RNF130 monoclonal antibody | Rat |
| GM-Tg-mg-IP1505-Ab-1/ GM-Tg-mg-IP1505-Ab-2 | Anti-Mouse RNF130 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1505-Ab-1/ GM-Tg-cynog-IP1505-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RNF130 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1505-Ab-1/ GM-Tg-felg-IP1505-Ab-2 | Anti-Feline RNF130 monoclonal antibody | Feline |
| GM-Tg-cang-IP1505-Ab-1/ GM-Tg-cang-IP1505-Ab-2 | Anti-Canine RNF130 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1505-Ab-1/ GM-Tg-bovg-IP1505-Ab-2 | Anti-Bovine RNF130 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1505-Ab-1/ GM-Tg-equg-IP1505-Ab-2 | Anti-Equine RNF130 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1505-Ab-1/ GM-Tg-hg-IP1505-Ab-2; GM-Tg-rg-IP1505-Ab-1/ GM-Tg-rg-IP1505-Ab-2; GM-Tg-mg-IP1505-Ab-1/ GM-Tg-mg-IP1505-Ab-2; GM-Tg-cynog-IP1505-Ab-1/ GM-Tg-cynog-IP1505-Ab-2; GM-Tg-felg-IP1505-Ab-1/ GM-Tg-felg-IP1505-Ab-2; GM-Tg-cang-IP1505-Ab-1/ GM-Tg-cang-IP1505-Ab-2; GM-Tg-bovg-IP1505-Ab-1/ GM-Tg-bovg-IP1505-Ab-2; GM-Tg-equg-IP1505-Ab-1/ GM-Tg-equg-IP1505-Ab-2 |
| Products Name | Anti-RNF130 monoclonal antibody |
| Format | mab |
| Target Name | RNF130 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RNF130 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1505-Ag-1 | Recombinant multi-species GOLI/ RNF130/ G1RZFP protein |
| ORF Viral Vector | pGMLPm003395 | mouse Rnf130 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003395 | mouse Rnf130 Lentivirus particle |
Target information
| Target ID | GM-IP1505 |
| Target Name | RNF130 |
| Gene ID | 55819,59044,652955,715356,474651,101085174,525735,100067162 |
| Gene Symbol and Synonyms | 2510042A13Rik,G1RP,G1RZFP,GOLIATH,GP,RNF130 |
| Uniprot Accession | Q86XS8,Q6Y290 |
| Uniprot Entry Name | GOLI_HUMAN,GOLI_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000113269 |
| Target Classification | N/A |
The target: RNF130, gene name: RNF130, also named as G1RZFP, GOLIATH, GP. The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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