Anti-RNF148 monoclonal antibody

Pre-made anti-RNF148 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RNF148/RNF148 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1511-Ab-1/ GM-Tg-hg-IP1511-Ab-2Anti-Human RNF148 monoclonal antibodyHuman
GM-Tg-rg-IP1511-Ab-1/ GM-Tg-rg-IP1511-Ab-2Anti-Rat RNF148 monoclonal antibodyRat
GM-Tg-mg-IP1511-Ab-1/ GM-Tg-mg-IP1511-Ab-2Anti-Mouse RNF148 monoclonal antibodyMouse
GM-Tg-cynog-IP1511-Ab-1/ GM-Tg-cynog-IP1511-Ab-2Anti-Cynomolgus/ Rhesus macaque RNF148 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1511-Ab-1/ GM-Tg-felg-IP1511-Ab-2Anti-Feline RNF148 monoclonal antibodyFeline
GM-Tg-cang-IP1511-Ab-1/ GM-Tg-cang-IP1511-Ab-2Anti-Canine RNF148 monoclonal antibodyCanine
GM-Tg-bovg-IP1511-Ab-1/ GM-Tg-bovg-IP1511-Ab-2Anti-Bovine RNF148 monoclonal antibodyBovine
GM-Tg-equg-IP1511-Ab-1/ GM-Tg-equg-IP1511-Ab-2Anti-Equine RNF148 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1511-Ab-1/ GM-Tg-hg-IP1511-Ab-2; GM-Tg-rg-IP1511-Ab-1/ GM-Tg-rg-IP1511-Ab-2;
GM-Tg-mg-IP1511-Ab-1/ GM-Tg-mg-IP1511-Ab-2; GM-Tg-cynog-IP1511-Ab-1/ GM-Tg-cynog-IP1511-Ab-2;
GM-Tg-felg-IP1511-Ab-1/ GM-Tg-felg-IP1511-Ab-2; GM-Tg-cang-IP1511-Ab-1/ GM-Tg-cang-IP1511-Ab-2;
GM-Tg-bovg-IP1511-Ab-1/ GM-Tg-bovg-IP1511-Ab-2; GM-Tg-equg-IP1511-Ab-1/ GM-Tg-equg-IP1511-Ab-2
Products NameAnti-RNF148 monoclonal antibody
Formatmab
Target NameRNF148
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RNF148 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1511-Ag-1Recombinant multi-species RN148/ RNF148 protein


    Target information

    Target IDGM-IP1511
    Target NameRNF148
    Gene ID378925,71300,681407,695090,475305,101091776,538888,100056342
    Gene Symbol and Synonyms4933432M07Rik,Greul3,RNF148
    Uniprot AccessionQ8N7C7,Q2TA44
    Uniprot Entry NameRN148_HUMAN,RN148_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000235631
    Target ClassificationN/A

    The target: RNF148, gene name: RNF148, also named as . Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and late endosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.