Anti-RNF167 monoclonal antibody

Pre-made anti-RNF167 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RNF167/RNF167 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1514-Ab-1/ GM-Tg-hg-IP1514-Ab-2Anti-Human RNF167 monoclonal antibodyHuman
GM-Tg-rg-IP1514-Ab-1/ GM-Tg-rg-IP1514-Ab-2Anti-Rat RNF167 monoclonal antibodyRat
GM-Tg-mg-IP1514-Ab-1/ GM-Tg-mg-IP1514-Ab-2Anti-Mouse RNF167 monoclonal antibodyMouse
GM-Tg-cynog-IP1514-Ab-1/ GM-Tg-cynog-IP1514-Ab-2Anti-Cynomolgus/ Rhesus macaque RNF167 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1514-Ab-1/ GM-Tg-felg-IP1514-Ab-2Anti-Feline RNF167 monoclonal antibodyFeline
GM-Tg-cang-IP1514-Ab-1/ GM-Tg-cang-IP1514-Ab-2Anti-Canine RNF167 monoclonal antibodyCanine
GM-Tg-bovg-IP1514-Ab-1/ GM-Tg-bovg-IP1514-Ab-2Anti-Bovine RNF167 monoclonal antibodyBovine
GM-Tg-equg-IP1514-Ab-1/ GM-Tg-equg-IP1514-Ab-2Anti-Equine RNF167 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1514-Ab-1/ GM-Tg-hg-IP1514-Ab-2; GM-Tg-rg-IP1514-Ab-1/ GM-Tg-rg-IP1514-Ab-2;
GM-Tg-mg-IP1514-Ab-1/ GM-Tg-mg-IP1514-Ab-2; GM-Tg-cynog-IP1514-Ab-1/ GM-Tg-cynog-IP1514-Ab-2;
GM-Tg-felg-IP1514-Ab-1/ GM-Tg-felg-IP1514-Ab-2; GM-Tg-cang-IP1514-Ab-1/ GM-Tg-cang-IP1514-Ab-2;
GM-Tg-bovg-IP1514-Ab-1/ GM-Tg-bovg-IP1514-Ab-2; GM-Tg-equg-IP1514-Ab-1/ GM-Tg-equg-IP1514-Ab-2
Products NameAnti-RNF167 monoclonal antibody
Formatmab
Target NameRNF167
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RNF167 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1514-Ag-1Recombinant multi-species RN167/ RNF167/ 5730408C10Rik protein


    Target information

    Target IDGM-IP1514
    Target NameRNF167
    Gene ID26001,70510,360554,710656,489456,101092063,616030,100061251
    Gene Symbol and Synonyms0610010G05Rik,5730408C10Rik,LP2254,RGD1305972,RING105,RNF167
    Uniprot AccessionQ9H6Y7,Q5XIL0
    Uniprot Entry NameRN167_HUMAN,RN167_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000108523
    Target ClassificationN/A

    The target: RNF167, gene name: RNF167, also named as 5730408C10Rik, LP2254, RING105. RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 [PubMed 16314844]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.