Anti-RNF215 monoclonal antibody

Pre-made anti-RNF215 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RNF215/RNF215 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1525-Ab-1/ GM-Tg-hg-IP1525-Ab-2 Anti-Human RNF215 monoclonal antibody Human
GM-Tg-rg-IP1525-Ab-1/ GM-Tg-rg-IP1525-Ab-2 Anti-Rat RNF215 monoclonal antibody Rat
GM-Tg-mg-IP1525-Ab-1/ GM-Tg-mg-IP1525-Ab-2 Anti-Mouse RNF215 monoclonal antibody Mouse
GM-Tg-cynog-IP1525-Ab-1/ GM-Tg-cynog-IP1525-Ab-2 Anti-Cynomolgus/ Rhesus macaque RNF215 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1525-Ab-1/ GM-Tg-felg-IP1525-Ab-2 Anti-Feline RNF215 monoclonal antibody Feline
GM-Tg-cang-IP1525-Ab-1/ GM-Tg-cang-IP1525-Ab-2 Anti-Canine RNF215 monoclonal antibody Canine
GM-Tg-bovg-IP1525-Ab-1/ GM-Tg-bovg-IP1525-Ab-2 Anti-Bovine RNF215 monoclonal antibody Bovine
GM-Tg-equg-IP1525-Ab-1/ GM-Tg-equg-IP1525-Ab-2 Anti-Equine RNF215 monoclonal antibody Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1525-Ab-1/ GM-Tg-hg-IP1525-Ab-2; GM-Tg-rg-IP1525-Ab-1/ GM-Tg-rg-IP1525-Ab-2;
GM-Tg-mg-IP1525-Ab-1/ GM-Tg-mg-IP1525-Ab-2; GM-Tg-cynog-IP1525-Ab-1/ GM-Tg-cynog-IP1525-Ab-2;
GM-Tg-felg-IP1525-Ab-1/ GM-Tg-felg-IP1525-Ab-2; GM-Tg-cang-IP1525-Ab-1/ GM-Tg-cang-IP1525-Ab-2;
GM-Tg-bovg-IP1525-Ab-1/ GM-Tg-bovg-IP1525-Ab-2; GM-Tg-equg-IP1525-Ab-1/ GM-Tg-equg-IP1525-Ab-2
Products Name Anti-RNF215 monoclonal antibody
Format mab
Target Name RNF215
Protein Sub-location Introcelluar Protein
Category of antibody
Derivation (species) Mouse
CH1+2+3 Isotype
(Receptor identification)		 IgG
Type of Light Chain (VD-LC) N/A
Expression platform Mammalian Expression
Bioactivity validation Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Tag Fc
Products description Pre-made anti-RNF215 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study



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    • Figure A: GeneMedi's GMP-h-p-tau181-Ab01 (Anti-human p-tau181 antibody) is validated to detect the GMP-h-p-tau181-Ag01 (p-tau181 antigen) in ELISA, EC50 = 25.26ng/ml.

    • Figure B: GeneMedi's GMP-h-p-tau217-Ab01 (Anti-human p-tau217 antibody) is validated to detect the GMP-h-p-tau217-Ag01 (p-tau217 antigen) in ELISA, EC50 = 25.85ng/ml.

    • Figure C: GeneMedi's GMP-h-p-tau231-Ab01 (Anti-human p-tau231 antibody) is validated to detect the GMP-h-p-tau231-Ag01 (p-tau231 antigen) in ELISA. EC50 = 64.34ng/ml.


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antigen GM-Tg-g-IP1525-Ag-1 Recombinant multi-species RN215/ RNF215 protein


    Target information

    Target ID GM-IP1525
    Target Name RNF215
    Gene ID 200312,71673,305478,715696,486351,101091482,530174,100063936
    Gene Symbol and Synonyms 0610009J22Rik,RGD1310738,RNF215
    Uniprot Accession Q9Y6U7
    Uniprot Entry Name RN215_HUMAN
    Protein Sub-location Introcelluar Protein
    Category
    Disease N/A
    Gene Ensembl ENSG00000099999
    Target Classification N/A

    The target: RNF215, gene name: RNF215, also named as . Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Golgi to vacuole transport; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be part of Golgi transport complex. Predicted to be active in endosome; membrane; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.