Anti-RNF24 monoclonal antibody

Pre-made anti-RNF24 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RNF24/RNF24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1529-Ab-1/ GM-Tg-hg-IP1529-Ab-2Anti-Human RNF24 monoclonal antibodyHuman
GM-Tg-rg-IP1529-Ab-1/ GM-Tg-rg-IP1529-Ab-2Anti-Rat RNF24 monoclonal antibodyRat
GM-Tg-mg-IP1529-Ab-1/ GM-Tg-mg-IP1529-Ab-2Anti-Mouse RNF24 monoclonal antibodyMouse
GM-Tg-cynog-IP1529-Ab-1/ GM-Tg-cynog-IP1529-Ab-2Anti-Cynomolgus/ Rhesus macaque RNF24 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1529-Ab-1/ GM-Tg-felg-IP1529-Ab-2Anti-Feline RNF24 monoclonal antibodyFeline
GM-Tg-cang-IP1529-Ab-1/ GM-Tg-cang-IP1529-Ab-2Anti-Canine RNF24 monoclonal antibodyCanine
GM-Tg-bovg-IP1529-Ab-1/ GM-Tg-bovg-IP1529-Ab-2Anti-Bovine RNF24 monoclonal antibodyBovine
GM-Tg-equg-IP1529-Ab-1/ GM-Tg-equg-IP1529-Ab-2Anti-Equine RNF24 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1529-Ab-1/ GM-Tg-hg-IP1529-Ab-2; GM-Tg-rg-IP1529-Ab-1/ GM-Tg-rg-IP1529-Ab-2;
GM-Tg-mg-IP1529-Ab-1/ GM-Tg-mg-IP1529-Ab-2; GM-Tg-cynog-IP1529-Ab-1/ GM-Tg-cynog-IP1529-Ab-2;
GM-Tg-felg-IP1529-Ab-1/ GM-Tg-felg-IP1529-Ab-2; GM-Tg-cang-IP1529-Ab-1/ GM-Tg-cang-IP1529-Ab-2;
GM-Tg-bovg-IP1529-Ab-1/ GM-Tg-bovg-IP1529-Ab-2; GM-Tg-equg-IP1529-Ab-1/ GM-Tg-equg-IP1529-Ab-2
Products NameAnti-RNF24 monoclonal antibody
Formatmab
Target NameRNF24
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RNF24 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1529-Ag-1Recombinant multi-species RNF24/ G1L protein


    Target information

    Target IDGM-IP1529
    Target NameRNF24
    Gene ID11237,51902,717693,607703,101085455,767991,100629353
    Gene Symbol and Synonyms2810473M14Rik,4930505A13Rik,D2Ertd504e,G1L,RNF24
    Uniprot AccessionQ9Y225
    Uniprot Entry NameRNF24_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000101236
    Target ClassificationN/A

    The target: RNF24, gene name: RNF24, also named as G1L. This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.