Anti-RNFT1 monoclonal antibody

Pre-made anti-RNFT1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RNFT1/RNFT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1531-Ab-1/ GM-Tg-hg-IP1531-Ab-2Anti-Human RNFT1 monoclonal antibodyHuman
GM-Tg-rg-IP1531-Ab-1/ GM-Tg-rg-IP1531-Ab-2Anti-Rat RNFT1 monoclonal antibodyRat
GM-Tg-mg-IP1531-Ab-1/ GM-Tg-mg-IP1531-Ab-2Anti-Mouse RNFT1 monoclonal antibodyMouse
GM-Tg-cynog-IP1531-Ab-1/ GM-Tg-cynog-IP1531-Ab-2Anti-Cynomolgus/ Rhesus macaque RNFT1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1531-Ab-1/ GM-Tg-felg-IP1531-Ab-2Anti-Feline RNFT1 monoclonal antibodyFeline
GM-Tg-cang-IP1531-Ab-1/ GM-Tg-cang-IP1531-Ab-2Anti-Canine RNFT1 monoclonal antibodyCanine
GM-Tg-bovg-IP1531-Ab-1/ GM-Tg-bovg-IP1531-Ab-2Anti-Bovine RNFT1 monoclonal antibodyBovine
GM-Tg-equg-IP1531-Ab-1/ GM-Tg-equg-IP1531-Ab-2Anti-Equine RNFT1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1531-Ab-1/ GM-Tg-hg-IP1531-Ab-2; GM-Tg-rg-IP1531-Ab-1/ GM-Tg-rg-IP1531-Ab-2;
GM-Tg-mg-IP1531-Ab-1/ GM-Tg-mg-IP1531-Ab-2; GM-Tg-cynog-IP1531-Ab-1/ GM-Tg-cynog-IP1531-Ab-2;
GM-Tg-felg-IP1531-Ab-1/ GM-Tg-felg-IP1531-Ab-2; GM-Tg-cang-IP1531-Ab-1/ GM-Tg-cang-IP1531-Ab-2;
GM-Tg-bovg-IP1531-Ab-1/ GM-Tg-bovg-IP1531-Ab-2; GM-Tg-equg-IP1531-Ab-1/ GM-Tg-equg-IP1531-Ab-2
Products NameAnti-RNFT1 monoclonal antibody
Formatmab
Target NameRNFT1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RNFT1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1531-Ag-1Recombinant multi-species RNFT1/ PTD016 protein


    Target information

    Target IDGM-IP1531
    Target NameRNFT1
    Gene ID51136,76892,360595,712052,480581,101092309,616080,100071124
    Gene Symbol and Synonyms0610013E23Rik,PTD016,RGD1562411,RNFT1,Rnft1-ps1
    Uniprot AccessionQ5M7Z0
    Uniprot Entry NameRNFT1_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000189050
    Target ClassificationN/A

    The target: RNFT1, gene name: RNFT1, also named as PTD016. Enables ubiquitin binding activity and ubiquitin protein ligase activity. Involved in positive regulation of ERAD pathway and protein autoubiquitination. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.