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Anti-RPL17 monoclonal antibody
Pre-made anti-RPL17 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPL17/RPL17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1538-Ab-1/ GM-Tg-hg-IP1538-Ab-2 | Anti-Human RPL17 monoclonal antibody | Human |
| GM-Tg-rg-IP1538-Ab-1/ GM-Tg-rg-IP1538-Ab-2 | Anti-Rat RPL17 monoclonal antibody | Rat |
| GM-Tg-mg-IP1538-Ab-1/ GM-Tg-mg-IP1538-Ab-2 | Anti-Mouse RPL17 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1538-Ab-1/ GM-Tg-cynog-IP1538-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPL17 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1538-Ab-1/ GM-Tg-felg-IP1538-Ab-2 | Anti-Feline RPL17 monoclonal antibody | Feline |
| GM-Tg-cang-IP1538-Ab-1/ GM-Tg-cang-IP1538-Ab-2 | Anti-Canine RPL17 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1538-Ab-1/ GM-Tg-bovg-IP1538-Ab-2 | Anti-Bovine RPL17 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1538-Ab-1/ GM-Tg-equg-IP1538-Ab-2 | Anti-Equine RPL17 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1538-Ab-1/ GM-Tg-hg-IP1538-Ab-2; GM-Tg-rg-IP1538-Ab-1/ GM-Tg-rg-IP1538-Ab-2; GM-Tg-mg-IP1538-Ab-1/ GM-Tg-mg-IP1538-Ab-2; GM-Tg-cynog-IP1538-Ab-1/ GM-Tg-cynog-IP1538-Ab-2; GM-Tg-felg-IP1538-Ab-1/ GM-Tg-felg-IP1538-Ab-2; GM-Tg-cang-IP1538-Ab-1/ GM-Tg-cang-IP1538-Ab-2; GM-Tg-bovg-IP1538-Ab-1/ GM-Tg-bovg-IP1538-Ab-2; GM-Tg-equg-IP1538-Ab-1/ GM-Tg-equg-IP1538-Ab-2 |
| Products Name | Anti-RPL17 monoclonal antibody |
| Format | mab |
| Target Name | RPL17 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPL17 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1538-Ag-1 | Recombinant multi-species RL17/ RPL17/ L17 protein |
| ORF Viral Vector | pGMLP002637 | human RPL17 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002637 | human RPL17 Lentivirus particle |
| ORF Viral Vector | pGMLPm001183 | mouse Rpl17 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001183 | mouse Rpl17 Lentivirus particle |
Target information
| Target ID | GM-IP1538 |
| Target Name | RPL17 |
| Gene ID | 6139,319195,291434,698967,480221,100169966,514046 |
| Gene Symbol and Synonyms | ASI,L17,PD-1,RPL17,RPL17L,RPL23,uL22 |
| Uniprot Accession | P18621,P24049,Q5XTY7,Q3T025 |
| Uniprot Entry Name | RL17_HUMAN,RL17_RAT,RL17_FELCA,RL17_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000265681 |
| Target Classification | N/A |
The target: RPL17, gene name: RPL17, also named as L17, PD-1, RPL23. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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