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Anti-RPL27A monoclonal antibody
Pre-made anti-RPL27A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPL27A/RPL27A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1542-Ab-1/ GM-Tg-hg-IP1542-Ab-2 | Anti-Human RPL27A monoclonal antibody | Human |
| GM-Tg-rg-IP1542-Ab-1/ GM-Tg-rg-IP1542-Ab-2 | Anti-Rat RPL27A monoclonal antibody | Rat |
| GM-Tg-mg-IP1542-Ab-1/ GM-Tg-mg-IP1542-Ab-2 | Anti-Mouse RPL27A monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1542-Ab-1/ GM-Tg-cynog-IP1542-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPL27A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1542-Ab-1/ GM-Tg-felg-IP1542-Ab-2 | Anti-Feline RPL27A monoclonal antibody | Feline |
| GM-Tg-cang-IP1542-Ab-1/ GM-Tg-cang-IP1542-Ab-2 | Anti-Canine RPL27A monoclonal antibody | Canine |
| GM-Tg-bovg-IP1542-Ab-1/ GM-Tg-bovg-IP1542-Ab-2 | Anti-Bovine RPL27A monoclonal antibody | Bovine |
| GM-Tg-equg-IP1542-Ab-1/ GM-Tg-equg-IP1542-Ab-2 | Anti-Equine RPL27A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1542-Ab-1/ GM-Tg-hg-IP1542-Ab-2; GM-Tg-rg-IP1542-Ab-1/ GM-Tg-rg-IP1542-Ab-2; GM-Tg-mg-IP1542-Ab-1/ GM-Tg-mg-IP1542-Ab-2; GM-Tg-cynog-IP1542-Ab-1/ GM-Tg-cynog-IP1542-Ab-2; GM-Tg-felg-IP1542-Ab-1/ GM-Tg-felg-IP1542-Ab-2; GM-Tg-cang-IP1542-Ab-1/ GM-Tg-cang-IP1542-Ab-2; GM-Tg-bovg-IP1542-Ab-1/ GM-Tg-bovg-IP1542-Ab-2; GM-Tg-equg-IP1542-Ab-1/ GM-Tg-equg-IP1542-Ab-2 |
| Products Name | Anti-RPL27A monoclonal antibody |
| Format | mab |
| Target Name | RPL27A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPL27A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1542-Ag-1 | Recombinant multi-species RL27A/ RPL27A/ L27A protein |
Target information
| Target ID | GM-IP1542 |
| Target Name | RPL27A |
| Gene ID | 6157,26451,293418,708863,611398,101084223,404190,100071004 |
| Gene Symbol and Synonyms | L27',L27A,L29,RPL27A,uL15 |
| Uniprot Accession | P46776,P18445,Q56K03 |
| Uniprot Entry Name | RL27A_HUMAN,RL27A_RAT,RL27A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000166441 |
| Target Classification | N/A |
The target: RPL27A, gene name: RPL27A, also named as L27A. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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