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Anti-RPL3 monoclonal antibody
Pre-made anti-RPL3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPL3/RPL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1544-Ab-1/ GM-Tg-hg-IP1544-Ab-2 | Anti-Human RPL3 monoclonal antibody | Human |
| GM-Tg-rg-IP1544-Ab-1/ GM-Tg-rg-IP1544-Ab-2 | Anti-Rat RPL3 monoclonal antibody | Rat |
| GM-Tg-mg-IP1544-Ab-1/ GM-Tg-mg-IP1544-Ab-2 | Anti-Mouse RPL3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1544-Ab-1/ GM-Tg-cynog-IP1544-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPL3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1544-Ab-1/ GM-Tg-felg-IP1544-Ab-2 | Anti-Feline RPL3 monoclonal antibody | Feline |
| GM-Tg-cang-IP1544-Ab-1/ GM-Tg-cang-IP1544-Ab-2 | Anti-Canine RPL3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1544-Ab-1/ GM-Tg-bovg-IP1544-Ab-2 | Anti-Bovine RPL3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1544-Ab-1/ GM-Tg-equg-IP1544-Ab-2 | Anti-Equine RPL3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1544-Ab-1/ GM-Tg-hg-IP1544-Ab-2; GM-Tg-rg-IP1544-Ab-1/ GM-Tg-rg-IP1544-Ab-2; GM-Tg-mg-IP1544-Ab-1/ GM-Tg-mg-IP1544-Ab-2; GM-Tg-cynog-IP1544-Ab-1/ GM-Tg-cynog-IP1544-Ab-2; GM-Tg-felg-IP1544-Ab-1/ GM-Tg-felg-IP1544-Ab-2; GM-Tg-cang-IP1544-Ab-1/ GM-Tg-cang-IP1544-Ab-2; GM-Tg-bovg-IP1544-Ab-1/ GM-Tg-bovg-IP1544-Ab-2; GM-Tg-equg-IP1544-Ab-1/ GM-Tg-equg-IP1544-Ab-2 |
| Products Name | Anti-RPL3 monoclonal antibody |
| Format | mab |
| Target Name | RPL3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPL3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1544-Ag-1 | Recombinant multi-species RL3/ RPL3/ ASC-1 protein |
| ORF Viral Vector | vGMLP000145 | human RPL3 Lentivirus particle |
| ORF Viral Vector | pGMLP000145 | human RPL3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001764 | mouse Rpl3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001764 | mouse Rpl3 Lentivirus particle |
Target information
| Target ID | GM-IP1544 |
| Target Name | RPL3 |
| Gene ID | 6122,27367,300079,707176,474504,101083352,282688,100070291 |
| Gene Symbol and Synonyms | ASC-1,F2,J1,L3,RPL3,TARBP-B,uL3 |
| Uniprot Accession | P39023,P21531,P39872 |
| Uniprot Entry Name | RL3_HUMAN,RL3_RAT,RL3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000100316 |
| Target Classification | N/A |
The target: RPL3, gene name: RPL3, also named as ASC-1, L3, TARBP-B. Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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