Anti-RPL35A monoclonal antibody
Pre-made anti-RPL35A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1547-Ab-1/ GM-Tg-hg-IP1547-Ab-2 | Anti-Human RPL35A monoclonal antibody | Human |
GM-Tg-rg-IP1547-Ab-1/ GM-Tg-rg-IP1547-Ab-2 | Anti-Rat RPL35A monoclonal antibody | Rat |
GM-Tg-mg-IP1547-Ab-1/ GM-Tg-mg-IP1547-Ab-2 | Anti-Mouse RPL35A monoclonal antibody | Mouse |
GM-Tg-cynog-IP1547-Ab-1/ GM-Tg-cynog-IP1547-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPL35A monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1547-Ab-1/ GM-Tg-felg-IP1547-Ab-2 | Anti-Feline RPL35A monoclonal antibody | Feline |
GM-Tg-cang-IP1547-Ab-1/ GM-Tg-cang-IP1547-Ab-2 | Anti-Canine RPL35A monoclonal antibody | Canine |
GM-Tg-bovg-IP1547-Ab-1/ GM-Tg-bovg-IP1547-Ab-2 | Anti-Bovine RPL35A monoclonal antibody | Bovine |
GM-Tg-equg-IP1547-Ab-1/ GM-Tg-equg-IP1547-Ab-2 | Anti-Equine RPL35A monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP1547-Ab-1/ GM-Tg-hg-IP1547-Ab-2; GM-Tg-rg-IP1547-Ab-1/ GM-Tg-rg-IP1547-Ab-2; GM-Tg-mg-IP1547-Ab-1/ GM-Tg-mg-IP1547-Ab-2; GM-Tg-cynog-IP1547-Ab-1/ GM-Tg-cynog-IP1547-Ab-2; GM-Tg-felg-IP1547-Ab-1/ GM-Tg-felg-IP1547-Ab-2; GM-Tg-cang-IP1547-Ab-1/ GM-Tg-cang-IP1547-Ab-2; GM-Tg-bovg-IP1547-Ab-1/ GM-Tg-bovg-IP1547-Ab-2; GM-Tg-equg-IP1547-Ab-1/ GM-Tg-equg-IP1547-Ab-2 |
Products Name | Anti-RPL35A monoclonal antibody |
Format | mab |
Target Name | RPL35A |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-RPL35A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP1547-Ag-1 | Recombinant multi-species RL35A/ RPL35A/ DBA5 protein |
ORF Viral Vector | pGMLP000403 | human RPL35A Lentivirus plasmid |
ORF Viral Vector | vGMLP000403 | human RPL35A Lentivirus particle |
ORF Viral Vector | pGMLPm000180 | mouse Rpl35a Lentivirus plasmid |
ORF Viral Vector | vGMLPm000180 | mouse Rpl35a Lentivirus particle |
Target information
Target ID | GM-IP1547 |
Target Name | RPL35A |
Gene ID | 6165,57808,57809,478597,101097338,506768,100034007 |
Gene Symbol and Synonyms | 2810431L15Rik,DBA5,eL33,L35A,Rpl35,RPL35A,Rpl35al1 |
Uniprot Accession | P18077,P04646,Q56JY1 |
Uniprot Entry Name | RL35A_HUMAN,RL35A_RAT,RL35A_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000182899 |
Target Classification | N/A |
The target: RPL35A, gene name: RPL35A, also named as DBA5, L35A, eL33. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L35AE family of ribosomal proteins. It is located in the cytoplasm. The rat protein has been shown to bind to both initiator and elongator tRNAs, and thus, it is located at the P site, or P and A sites, of the ribosome. Although this gene was originally mapped to chromosome 18, it has been established that it is located at 3q29-qter. Alternative splicing results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Oct 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.