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Anti-RPN2 monoclonal antibody
Pre-made anti-RPN2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPN2/RPN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1551-Ab-1/ GM-Tg-hg-IP1551-Ab-2 | Anti-Human RPN2 monoclonal antibody | Human |
| GM-Tg-rg-IP1551-Ab-1/ GM-Tg-rg-IP1551-Ab-2 | Anti-Rat RPN2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1551-Ab-1/ GM-Tg-mg-IP1551-Ab-2 | Anti-Mouse RPN2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1551-Ab-1/ GM-Tg-cynog-IP1551-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPN2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1551-Ab-1/ GM-Tg-felg-IP1551-Ab-2 | Anti-Feline RPN2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1551-Ab-1/ GM-Tg-cang-IP1551-Ab-2 | Anti-Canine RPN2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1551-Ab-1/ GM-Tg-bovg-IP1551-Ab-2 | Anti-Bovine RPN2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1551-Ab-1/ GM-Tg-equg-IP1551-Ab-2 | Anti-Equine RPN2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1551-Ab-1/ GM-Tg-hg-IP1551-Ab-2; GM-Tg-rg-IP1551-Ab-1/ GM-Tg-rg-IP1551-Ab-2; GM-Tg-mg-IP1551-Ab-1/ GM-Tg-mg-IP1551-Ab-2; GM-Tg-cynog-IP1551-Ab-1/ GM-Tg-cynog-IP1551-Ab-2; GM-Tg-felg-IP1551-Ab-1/ GM-Tg-felg-IP1551-Ab-2; GM-Tg-cang-IP1551-Ab-1/ GM-Tg-cang-IP1551-Ab-2; GM-Tg-bovg-IP1551-Ab-1/ GM-Tg-bovg-IP1551-Ab-2; GM-Tg-equg-IP1551-Ab-1/ GM-Tg-equg-IP1551-Ab-2 |
| Products Name | Anti-RPN2 monoclonal antibody |
| Format | mab |
| Target Name | RPN2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPN2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1551-Ag-1 | Recombinant multi-species RPN2/ RIBIIR/ RPN-II protein |
Target information
| Target ID | GM-IP1551 |
| Target Name | RPN2 |
| Gene ID | 6185,20014,64701,708971,477223,101101302,534231,100069839 |
| Gene Symbol and Synonyms | 1300012C06Rik,RIBIIR,Rpn-2,RPN-II,RPN2,RPNII,SWP1 |
| Uniprot Accession | P04844,P25235,F1PCT7,Q3SZI6 |
| Uniprot Entry Name | RPN2_HUMAN,RPN2_RAT,RPN2_CANLF,RPN2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000118705 |
| Target Classification | N/A |
The target: RPN2, gene name: RPN2, also named as RIBIIR, RPN-II, RPNII, SWP1. This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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