- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SACM1L monoclonal antibody
Pre-made anti-SACM1L monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SACM1L/SACM1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1569-Ab-1/ GM-Tg-hg-IP1569-Ab-2 | Anti-Human SACM1L monoclonal antibody | Human |
| GM-Tg-rg-IP1569-Ab-1/ GM-Tg-rg-IP1569-Ab-2 | Anti-Rat SACM1L monoclonal antibody | Rat |
| GM-Tg-mg-IP1569-Ab-1/ GM-Tg-mg-IP1569-Ab-2 | Anti-Mouse SACM1L monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1569-Ab-1/ GM-Tg-cynog-IP1569-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SACM1L monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1569-Ab-1/ GM-Tg-felg-IP1569-Ab-2 | Anti-Feline SACM1L monoclonal antibody | Feline |
| GM-Tg-cang-IP1569-Ab-1/ GM-Tg-cang-IP1569-Ab-2 | Anti-Canine SACM1L monoclonal antibody | Canine |
| GM-Tg-bovg-IP1569-Ab-1/ GM-Tg-bovg-IP1569-Ab-2 | Anti-Bovine SACM1L monoclonal antibody | Bovine |
| GM-Tg-equg-IP1569-Ab-1/ GM-Tg-equg-IP1569-Ab-2 | Anti-Equine SACM1L monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1569-Ab-1/ GM-Tg-hg-IP1569-Ab-2; GM-Tg-rg-IP1569-Ab-1/ GM-Tg-rg-IP1569-Ab-2; GM-Tg-mg-IP1569-Ab-1/ GM-Tg-mg-IP1569-Ab-2; GM-Tg-cynog-IP1569-Ab-1/ GM-Tg-cynog-IP1569-Ab-2; GM-Tg-felg-IP1569-Ab-1/ GM-Tg-felg-IP1569-Ab-2; GM-Tg-cang-IP1569-Ab-1/ GM-Tg-cang-IP1569-Ab-2; GM-Tg-bovg-IP1569-Ab-1/ GM-Tg-bovg-IP1569-Ab-2; GM-Tg-equg-IP1569-Ab-1/ GM-Tg-equg-IP1569-Ab-2 |
| Products Name | Anti-SACM1L monoclonal antibody |
| Format | mab |
| Target Name | SACM1L |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SACM1L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1569-Ag-1 | Recombinant multi-species SAC1/ SACM1L protein |
Target information
| Target ID | GM-IP1569 |
| Target Name | SACM1L |
| Gene ID | 22908,83493,116482,714107,484795,101082728,530577,100065601 |
| Gene Symbol and Synonyms | mKIAA0851,SAC1,Sac1p,SACM1L |
| Uniprot Accession | Q9NTJ5,Q9ES21,A6QL88 |
| Uniprot Entry Name | SAC1_HUMAN,SAC1_RAT,SAC1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000211456 |
| Target Classification | N/A |
The target: SACM1L, gene name: SACM1L, also named as SAC1. This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame, downstream translation termination codon via a stop codon readthrough mechanism.[provided by RefSeq, Dec 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
