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Anti-SC5D monoclonal antibody
Pre-made anti-SC5D monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SC5D/SC5D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1575-Ab-1/ GM-Tg-hg-IP1575-Ab-2 | Anti-Human SC5D monoclonal antibody | Human |
| GM-Tg-rg-IP1575-Ab-1/ GM-Tg-rg-IP1575-Ab-2 | Anti-Rat SC5D monoclonal antibody | Rat |
| GM-Tg-mg-IP1575-Ab-1/ GM-Tg-mg-IP1575-Ab-2 | Anti-Mouse SC5D monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1575-Ab-1/ GM-Tg-cynog-IP1575-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SC5D monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1575-Ab-1/ GM-Tg-felg-IP1575-Ab-2 | Anti-Feline SC5D monoclonal antibody | Feline |
| GM-Tg-cang-IP1575-Ab-1/ GM-Tg-cang-IP1575-Ab-2 | Anti-Canine SC5D monoclonal antibody | Canine |
| GM-Tg-bovg-IP1575-Ab-1/ GM-Tg-bovg-IP1575-Ab-2 | Anti-Bovine SC5D monoclonal antibody | Bovine |
| GM-Tg-equg-IP1575-Ab-1/ GM-Tg-equg-IP1575-Ab-2 | Anti-Equine SC5D monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1575-Ab-1/ GM-Tg-hg-IP1575-Ab-2; GM-Tg-rg-IP1575-Ab-1/ GM-Tg-rg-IP1575-Ab-2; GM-Tg-mg-IP1575-Ab-1/ GM-Tg-mg-IP1575-Ab-2; GM-Tg-cynog-IP1575-Ab-1/ GM-Tg-cynog-IP1575-Ab-2; GM-Tg-felg-IP1575-Ab-1/ GM-Tg-felg-IP1575-Ab-2; GM-Tg-cang-IP1575-Ab-1/ GM-Tg-cang-IP1575-Ab-2; GM-Tg-bovg-IP1575-Ab-1/ GM-Tg-bovg-IP1575-Ab-2; GM-Tg-equg-IP1575-Ab-1/ GM-Tg-equg-IP1575-Ab-2 |
| Products Name | Anti-SC5D monoclonal antibody |
| Format | mab |
| Target Name | SC5D |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SC5D monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1575-Ag-1 | Recombinant multi-species SC5D/ ERG3/ S5DESL protein |
| ORF Viral Vector | vGMLP001844 | human SC5D Lentivirus particle |
| ORF Viral Vector | pGMLP001844 | human SC5D Lentivirus plasmid |
| ORF Viral Vector | vGMLP001019 | human SC5D Lentivirus particle |
| ORF Viral Vector | pGMLP001019 | human SC5D Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004499 | mouse Sc5d Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004804 | mouse Sc5d Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004499 | mouse Sc5d Lentivirus particle |
| ORF Viral Vector | vGMLPm004804 | mouse Sc5d Lentivirus particle |
Target information
| Target ID | GM-IP1575 |
| Target Name | SC5D |
| Gene ID | 6309,235293,114100,706827,610411,101099997,525154,100063543 |
| Gene Symbol and Synonyms | A830037K02,A830073K23Rik,ERG3,S5DES,SC5D,SC5DL |
| Uniprot Accession | O75845,Q9EQS5 |
| Uniprot Entry Name | SC5D_HUMAN,SC5D_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000109929 |
| Target Classification | N/A |
The target: SC5D, gene name: SC5D, also named as ERG3, S5DESL, SC5D. This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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