Anti-SCARA3 monoclonal antibody

Pre-made anti-SCARA3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SCARA3/SCARA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1580-Ab-1/ GM-Tg-hg-IP1580-Ab-2Anti-Human SCARA3 monoclonal antibodyHuman
GM-Tg-rg-IP1580-Ab-1/ GM-Tg-rg-IP1580-Ab-2Anti-Rat SCARA3 monoclonal antibodyRat
GM-Tg-mg-IP1580-Ab-1/ GM-Tg-mg-IP1580-Ab-2Anti-Mouse SCARA3 monoclonal antibodyMouse
GM-Tg-cynog-IP1580-Ab-1/ GM-Tg-cynog-IP1580-Ab-2Anti-Cynomolgus/ Rhesus macaque SCARA3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1580-Ab-1/ GM-Tg-felg-IP1580-Ab-2Anti-Feline SCARA3 monoclonal antibodyFeline
GM-Tg-cang-IP1580-Ab-1/ GM-Tg-cang-IP1580-Ab-2Anti-Canine SCARA3 monoclonal antibodyCanine
GM-Tg-bovg-IP1580-Ab-1/ GM-Tg-bovg-IP1580-Ab-2Anti-Bovine SCARA3 monoclonal antibodyBovine
GM-Tg-equg-IP1580-Ab-1/ GM-Tg-equg-IP1580-Ab-2Anti-Equine SCARA3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1580-Ab-1/ GM-Tg-hg-IP1580-Ab-2; GM-Tg-rg-IP1580-Ab-1/ GM-Tg-rg-IP1580-Ab-2;
GM-Tg-mg-IP1580-Ab-1/ GM-Tg-mg-IP1580-Ab-2; GM-Tg-cynog-IP1580-Ab-1/ GM-Tg-cynog-IP1580-Ab-2;
GM-Tg-felg-IP1580-Ab-1/ GM-Tg-felg-IP1580-Ab-2; GM-Tg-cang-IP1580-Ab-1/ GM-Tg-cang-IP1580-Ab-2;
GM-Tg-bovg-IP1580-Ab-1/ GM-Tg-bovg-IP1580-Ab-2; GM-Tg-equg-IP1580-Ab-1/ GM-Tg-equg-IP1580-Ab-2
Products NameAnti-SCARA3 monoclonal antibody
Formatmab
Target NameSCARA3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SCARA3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1580-Ag-1Recombinant multi-species SCAR3/ SCARA3/ APC7 protein


    Target information

    Target IDGM-IP1580
    Target NameSCARA3
    Gene ID51435,219151,364405,718263,486099,101080280,541156,100060652
    Gene Symbol and SynonymsAPC7,C130058N24Rik,CSR,CSR1,MSLR1,MSRL1,SCARA3
    Uniprot AccessionQ6AZY7
    Uniprot Entry NameSCAR3_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000168077
    Target ClassificationN/A

    The target: SCARA3, gene name: SCARA3, also named as APC7, CSR, CSR1, MSLR1, MSRL1. This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.