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Anti-SCD5 monoclonal antibody
Pre-made anti-SCD5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SCD5/SCD5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1583-Ab-1/ GM-Tg-hg-IP1583-Ab-2 | Anti-Human SCD5 monoclonal antibody | Human |
| GM-Tg-rg-IP1583-Ab-1/ GM-Tg-rg-IP1583-Ab-2 | Anti-Rat SCD5 monoclonal antibody | Rat |
| GM-Tg-mg-IP1583-Ab-1/ GM-Tg-mg-IP1583-Ab-2 | Anti-Mouse SCD5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1583-Ab-1/ GM-Tg-cynog-IP1583-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SCD5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1583-Ab-1/ GM-Tg-felg-IP1583-Ab-2 | Anti-Feline SCD5 monoclonal antibody | Feline |
| GM-Tg-cang-IP1583-Ab-1/ GM-Tg-cang-IP1583-Ab-2 | Anti-Canine SCD5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1583-Ab-1/ GM-Tg-bovg-IP1583-Ab-2 | Anti-Bovine SCD5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1583-Ab-1/ GM-Tg-equg-IP1583-Ab-2 | Anti-Equine SCD5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1583-Ab-1/ GM-Tg-hg-IP1583-Ab-2; GM-Tg-rg-IP1583-Ab-1/ GM-Tg-rg-IP1583-Ab-2; GM-Tg-mg-IP1583-Ab-1/ GM-Tg-mg-IP1583-Ab-2; GM-Tg-cynog-IP1583-Ab-1/ GM-Tg-cynog-IP1583-Ab-2; GM-Tg-felg-IP1583-Ab-1/ GM-Tg-felg-IP1583-Ab-2; GM-Tg-cang-IP1583-Ab-1/ GM-Tg-cang-IP1583-Ab-2; GM-Tg-bovg-IP1583-Ab-1/ GM-Tg-bovg-IP1583-Ab-2; GM-Tg-equg-IP1583-Ab-1/ GM-Tg-equg-IP1583-Ab-2 |
| Products Name | Anti-SCD5 monoclonal antibody |
| Format | mab |
| Target Name | SCD5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SCD5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1583-Ag-1 | Recombinant multi-species SCD5/ ACOD4/ FADS4 protein |
Target information
| Target ID | GM-IP1583 |
| Target Name | SCD5 |
| Gene ID | 79966,666417,694079,487831,101090611,617419,100060968 |
| Gene Symbol and Synonyms | ACOD4,DFNA79,EG666417,FADS4,Gm8091,HSCD5,SCD2,SCD4,SCD5 |
| Uniprot Accession | Q86SK9,Q2KIA4 |
| Uniprot Entry Name | SCD5_HUMAN,SCD5_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000145284 |
| Target Classification | N/A |
The target: SCD5, gene name: SCD5, also named as ACOD4, FADS4, HSCD5, SCD2, SCD4. Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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