Anti-SCIMP monoclonal antibody

Pre-made anti-SCIMP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SCIMP/SCIMP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1584-Ab-1/ GM-Tg-hg-IP1584-Ab-2Anti-Human SCIMP monoclonal antibodyHuman
GM-Tg-rg-IP1584-Ab-1/ GM-Tg-rg-IP1584-Ab-2Anti-Rat SCIMP monoclonal antibodyRat
GM-Tg-mg-IP1584-Ab-1/ GM-Tg-mg-IP1584-Ab-2Anti-Mouse SCIMP monoclonal antibodyMouse
GM-Tg-cynog-IP1584-Ab-1/ GM-Tg-cynog-IP1584-Ab-2Anti-Cynomolgus/ Rhesus macaque SCIMP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1584-Ab-1/ GM-Tg-felg-IP1584-Ab-2Anti-Feline SCIMP monoclonal antibodyFeline
GM-Tg-cang-IP1584-Ab-1/ GM-Tg-cang-IP1584-Ab-2Anti-Canine SCIMP monoclonal antibodyCanine
GM-Tg-bovg-IP1584-Ab-1/ GM-Tg-bovg-IP1584-Ab-2Anti-Bovine SCIMP monoclonal antibodyBovine
GM-Tg-equg-IP1584-Ab-1/ GM-Tg-equg-IP1584-Ab-2Anti-Equine SCIMP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1584-Ab-1/ GM-Tg-hg-IP1584-Ab-2; GM-Tg-rg-IP1584-Ab-1/ GM-Tg-rg-IP1584-Ab-2;
GM-Tg-mg-IP1584-Ab-1/ GM-Tg-mg-IP1584-Ab-2; GM-Tg-cynog-IP1584-Ab-1/ GM-Tg-cynog-IP1584-Ab-2;
GM-Tg-felg-IP1584-Ab-1/ GM-Tg-felg-IP1584-Ab-2; GM-Tg-cang-IP1584-Ab-1/ GM-Tg-cang-IP1584-Ab-2;
GM-Tg-bovg-IP1584-Ab-1/ GM-Tg-bovg-IP1584-Ab-2; GM-Tg-equg-IP1584-Ab-1/ GM-Tg-equg-IP1584-Ab-2
Products NameAnti-SCIMP monoclonal antibody
Formatmab
Target NameSCIMP
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SCIMP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1584-Ag-1Recombinant multi-species SCIMP/ C17orf87/ UNQ5783 protein


    Target information

    Target IDGM-IP1584
    Target NameSCIMP
    Gene ID388325,327957,691993,721635,607322,101090559,100848290,100629451
    Gene Symbol and SynonymsA430084P05Rik,C17orf87,C5H17orf87,SCIMP,UNQ5783
    Uniprot AccessionQ6UWF3
    Uniprot Entry NameSCIMP_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000161929
    Target ClassificationN/A

    The target: SCIMP, gene name: SCIMP, also named as C17orf87, UNQ5783. This gene encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and is localized in the immunologic synapse. The encoded protein is involved in major histocompatibility complex class II signal transduction and immune synapse formation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.