Anti-SCLY monoclonal antibody

Pre-made anti-SCLY monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SCLY/SCLY products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1585-Ab-1/ GM-Tg-hg-IP1585-Ab-2Anti-Human SCLY monoclonal antibodyHuman
GM-Tg-rg-IP1585-Ab-1/ GM-Tg-rg-IP1585-Ab-2Anti-Rat SCLY monoclonal antibodyRat
GM-Tg-mg-IP1585-Ab-1/ GM-Tg-mg-IP1585-Ab-2Anti-Mouse SCLY monoclonal antibodyMouse
GM-Tg-cynog-IP1585-Ab-1/ GM-Tg-cynog-IP1585-Ab-2Anti-Cynomolgus/ Rhesus macaque SCLY monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1585-Ab-1/ GM-Tg-felg-IP1585-Ab-2Anti-Feline SCLY monoclonal antibodyFeline
GM-Tg-cang-IP1585-Ab-1/ GM-Tg-cang-IP1585-Ab-2Anti-Canine SCLY monoclonal antibodyCanine
GM-Tg-bovg-IP1585-Ab-1/ GM-Tg-bovg-IP1585-Ab-2Anti-Bovine SCLY monoclonal antibodyBovine
GM-Tg-equg-IP1585-Ab-1/ GM-Tg-equg-IP1585-Ab-2Anti-Equine SCLY monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1585-Ab-1/ GM-Tg-hg-IP1585-Ab-2; GM-Tg-rg-IP1585-Ab-1/ GM-Tg-rg-IP1585-Ab-2;
GM-Tg-mg-IP1585-Ab-1/ GM-Tg-mg-IP1585-Ab-2; GM-Tg-cynog-IP1585-Ab-1/ GM-Tg-cynog-IP1585-Ab-2;
GM-Tg-felg-IP1585-Ab-1/ GM-Tg-felg-IP1585-Ab-2; GM-Tg-cang-IP1585-Ab-1/ GM-Tg-cang-IP1585-Ab-2;
GM-Tg-bovg-IP1585-Ab-1/ GM-Tg-bovg-IP1585-Ab-2; GM-Tg-equg-IP1585-Ab-1/ GM-Tg-equg-IP1585-Ab-2
Products NameAnti-SCLY monoclonal antibody
Formatmab
Target NameSCLY
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SCLY monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1585-Ag-1Recombinant multi-species SCLY/ SCL/ hSCL protein


    Target information

    Target IDGM-IP1585
    Target NameSCLY
    Gene ID51540,50880,363285,695511,477422,101088098,790815,100066596
    Gene Symbol and SynonymsA930015N15Rik,hSCL,mSCL,SCL,SCLY,Scly1,Scly2
    Uniprot AccessionQ96I15,Q68FT9,A2VDS1
    Uniprot Entry NameSCLY_HUMAN,SCLY_RAT,SCLY_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132330
    Target ClassificationN/A

    The target: SCLY, gene name: SCLY, also named as SCL, hSCL. Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.