Anti-SCN10A monoclonal antibody

Pre-made anti-SCN10A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SCN10A/SCN10A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1586-Ab-1/ GM-Tg-hg-IP1586-Ab-2Anti-Human SCN10A monoclonal antibodyHuman
GM-Tg-rg-IP1586-Ab-1/ GM-Tg-rg-IP1586-Ab-2Anti-Rat SCN10A monoclonal antibodyRat
GM-Tg-mg-IP1586-Ab-1/ GM-Tg-mg-IP1586-Ab-2Anti-Mouse SCN10A monoclonal antibodyMouse
GM-Tg-cynog-IP1586-Ab-1/ GM-Tg-cynog-IP1586-Ab-2Anti-Cynomolgus/ Rhesus macaque SCN10A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1586-Ab-1/ GM-Tg-felg-IP1586-Ab-2Anti-Feline SCN10A monoclonal antibodyFeline
GM-Tg-cang-IP1586-Ab-1/ GM-Tg-cang-IP1586-Ab-2Anti-Canine SCN10A monoclonal antibodyCanine
GM-Tg-bovg-IP1586-Ab-1/ GM-Tg-bovg-IP1586-Ab-2Anti-Bovine SCN10A monoclonal antibodyBovine
GM-Tg-equg-IP1586-Ab-1/ GM-Tg-equg-IP1586-Ab-2Anti-Equine SCN10A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1586-Ab-1/ GM-Tg-hg-IP1586-Ab-2; GM-Tg-rg-IP1586-Ab-1/ GM-Tg-rg-IP1586-Ab-2;
GM-Tg-mg-IP1586-Ab-1/ GM-Tg-mg-IP1586-Ab-2; GM-Tg-cynog-IP1586-Ab-1/ GM-Tg-cynog-IP1586-Ab-2;
GM-Tg-felg-IP1586-Ab-1/ GM-Tg-felg-IP1586-Ab-2; GM-Tg-cang-IP1586-Ab-1/ GM-Tg-cang-IP1586-Ab-2;
GM-Tg-bovg-IP1586-Ab-1/ GM-Tg-bovg-IP1586-Ab-2; GM-Tg-equg-IP1586-Ab-1/ GM-Tg-equg-IP1586-Ab-2
Products NameAnti-SCN10A monoclonal antibody
Formatmab
Target NameSCN10A
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SCN10A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1586-Ag-1Recombinant multi-species SCNAA/ SCN10A/ FEPS2 protein


    Target information

    Target IDGM-IP1586
    Target NameSCN10A
    Gene ID6336,20264,29571,694962,477026,101085569,100299477,100055493
    Gene Symbol and SynonymsFEPS2,Na(V)1.8,Nav1.8,PN3,SCN10A,SNS
    Uniprot AccessionQ9Y5Y9,Q62968,O46669
    Uniprot Entry NameSCNAA_HUMAN,SCNAA_RAT,SCNAA_CANLF
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000185313
    Target ClassificationIon Channel

    The target: SCN10A, gene name: SCN10A, also named as FEPS2, Nav1.8, PN3, SNS, hPN3. The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.