Anti-SEC61A2 monoclonal antibody

Pre-made anti-SEC61A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SEC61A2/SEC61A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1598-Ab-1/ GM-Tg-hg-IP1598-Ab-2Anti-Human SEC61A2 monoclonal antibodyHuman
GM-Tg-rg-IP1598-Ab-1/ GM-Tg-rg-IP1598-Ab-2Anti-Rat SEC61A2 monoclonal antibodyRat
GM-Tg-mg-IP1598-Ab-1/ GM-Tg-mg-IP1598-Ab-2Anti-Mouse SEC61A2 monoclonal antibodyMouse
GM-Tg-cynog-IP1598-Ab-1/ GM-Tg-cynog-IP1598-Ab-2Anti-Cynomolgus/ Rhesus macaque SEC61A2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1598-Ab-1/ GM-Tg-felg-IP1598-Ab-2Anti-Feline SEC61A2 monoclonal antibodyFeline
GM-Tg-cang-IP1598-Ab-1/ GM-Tg-cang-IP1598-Ab-2Anti-Canine SEC61A2 monoclonal antibodyCanine
GM-Tg-bovg-IP1598-Ab-1/ GM-Tg-bovg-IP1598-Ab-2Anti-Bovine SEC61A2 monoclonal antibodyBovine
GM-Tg-equg-IP1598-Ab-1/ GM-Tg-equg-IP1598-Ab-2Anti-Equine SEC61A2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1598-Ab-1/ GM-Tg-hg-IP1598-Ab-2; GM-Tg-rg-IP1598-Ab-1/ GM-Tg-rg-IP1598-Ab-2;
GM-Tg-mg-IP1598-Ab-1/ GM-Tg-mg-IP1598-Ab-2; GM-Tg-cynog-IP1598-Ab-1/ GM-Tg-cynog-IP1598-Ab-2;
GM-Tg-felg-IP1598-Ab-1/ GM-Tg-felg-IP1598-Ab-2; GM-Tg-cang-IP1598-Ab-1/ GM-Tg-cang-IP1598-Ab-2;
GM-Tg-bovg-IP1598-Ab-1/ GM-Tg-bovg-IP1598-Ab-2; GM-Tg-equg-IP1598-Ab-1/ GM-Tg-equg-IP1598-Ab-2
Products NameAnti-SEC61A2 monoclonal antibody
Formatmab
Target NameSEC61A2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SEC61A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1598-Ag-1Recombinant multi-species S61A2/ SEC61A2 protein


    Target information

    Target IDGM-IP1598
    Target NameSEC61A2
    Gene ID55176,57743,361273,100427731,478007,101086402,614128,100069336
    Gene Symbol and SynonymsSEC61A2
    Uniprot AccessionQ9H9S3,Q2KHX4
    Uniprot Entry NameS61A2_HUMAN,S61A2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000065665
    Target ClassificationN/A

    The target: SEC61A2, gene name: SEC61A2, also named as . The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.