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Anti-SEC62 monoclonal antibody
Pre-made anti-SEC62 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SEC62/SEC62 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1601-Ab-1/ GM-Tg-hg-IP1601-Ab-2 | Anti-Human SEC62 monoclonal antibody | Human |
| GM-Tg-rg-IP1601-Ab-1/ GM-Tg-rg-IP1601-Ab-2 | Anti-Rat SEC62 monoclonal antibody | Rat |
| GM-Tg-mg-IP1601-Ab-1/ GM-Tg-mg-IP1601-Ab-2 | Anti-Mouse SEC62 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1601-Ab-1/ GM-Tg-cynog-IP1601-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SEC62 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1601-Ab-1/ GM-Tg-felg-IP1601-Ab-2 | Anti-Feline SEC62 monoclonal antibody | Feline |
| GM-Tg-cang-IP1601-Ab-1/ GM-Tg-cang-IP1601-Ab-2 | Anti-Canine SEC62 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1601-Ab-1/ GM-Tg-bovg-IP1601-Ab-2 | Anti-Bovine SEC62 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1601-Ab-1/ GM-Tg-equg-IP1601-Ab-2 | Anti-Equine SEC62 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1601-Ab-1/ GM-Tg-hg-IP1601-Ab-2; GM-Tg-rg-IP1601-Ab-1/ GM-Tg-rg-IP1601-Ab-2; GM-Tg-mg-IP1601-Ab-1/ GM-Tg-mg-IP1601-Ab-2; GM-Tg-cynog-IP1601-Ab-1/ GM-Tg-cynog-IP1601-Ab-2; GM-Tg-felg-IP1601-Ab-1/ GM-Tg-felg-IP1601-Ab-2; GM-Tg-cang-IP1601-Ab-1/ GM-Tg-cang-IP1601-Ab-2; GM-Tg-bovg-IP1601-Ab-1/ GM-Tg-bovg-IP1601-Ab-2; GM-Tg-equg-IP1601-Ab-1/ GM-Tg-equg-IP1601-Ab-2 |
| Products Name | Anti-SEC62 monoclonal antibody |
| Format | mab |
| Target Name | SEC62 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SEC62 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1601-Ag-1 | Recombinant multi-species SEC62/ Dtrp1/ HTP1 protein |
Target information
| Target ID | GM-IP1601 |
| Target Name | SEC62 |
| Gene ID | 7095,69276,294912,696989,609416,101088021,538938,100063496 |
| Gene Symbol and Synonyms | 3100002M17Rik,Ab2-292,Dtrp1,HTP1,SEC62,TLOC1,TP-1 |
| Uniprot Accession | Q99442,P82009 |
| Uniprot Entry Name | SEC62_HUMAN,SEC62_CANLF |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000008952 |
| Target Classification | N/A |
The target: SEC62, gene name: SEC62, also named as Dtrp1, HTP1, TLOC1, TP-1. The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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