Anti-SEMA4C monoclonal antibody

Pre-made anti-SEMA4C monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SEMA4C/SEMA4C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1606-Ab-1/ GM-Tg-hg-IP1606-Ab-2Anti-Human SEMA4C monoclonal antibodyHuman
GM-Tg-rg-IP1606-Ab-1/ GM-Tg-rg-IP1606-Ab-2Anti-Rat SEMA4C monoclonal antibodyRat
GM-Tg-mg-IP1606-Ab-1/ GM-Tg-mg-IP1606-Ab-2Anti-Mouse SEMA4C monoclonal antibodyMouse
GM-Tg-cynog-IP1606-Ab-1/ GM-Tg-cynog-IP1606-Ab-2Anti-Cynomolgus/ Rhesus macaque SEMA4C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1606-Ab-1/ GM-Tg-felg-IP1606-Ab-2Anti-Feline SEMA4C monoclonal antibodyFeline
GM-Tg-cang-IP1606-Ab-1/ GM-Tg-cang-IP1606-Ab-2Anti-Canine SEMA4C monoclonal antibodyCanine
GM-Tg-bovg-IP1606-Ab-1/ GM-Tg-bovg-IP1606-Ab-2Anti-Bovine SEMA4C monoclonal antibodyBovine
GM-Tg-equg-IP1606-Ab-1/ GM-Tg-equg-IP1606-Ab-2Anti-Equine SEMA4C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1606-Ab-1/ GM-Tg-hg-IP1606-Ab-2; GM-Tg-rg-IP1606-Ab-1/ GM-Tg-rg-IP1606-Ab-2;
GM-Tg-mg-IP1606-Ab-1/ GM-Tg-mg-IP1606-Ab-2; GM-Tg-cynog-IP1606-Ab-1/ GM-Tg-cynog-IP1606-Ab-2;
GM-Tg-felg-IP1606-Ab-1/ GM-Tg-felg-IP1606-Ab-2; GM-Tg-cang-IP1606-Ab-1/ GM-Tg-cang-IP1606-Ab-2;
GM-Tg-bovg-IP1606-Ab-1/ GM-Tg-bovg-IP1606-Ab-2; GM-Tg-equg-IP1606-Ab-1/ GM-Tg-equg-IP1606-Ab-2
Products NameAnti-SEMA4C monoclonal antibody
Formatmab
Target NameSEMA4C
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SEMA4C monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1606-Ag-1Recombinant multi-species SEM4C/ SEMA4C/ M-SEMA-F protein


    Target information

    Target IDGM-IP1606
    Target NameSEMA4C
    Gene ID54910,20353,301346,707024,481343,101091276,526028,100146410
    Gene Symbol and SynonymsM-Sema F,M-SEMA-F,RGD1562837,sema I,SEMA4C,SEMACL1,SEMAF,SEMAI
    Uniprot AccessionQ9C0C4
    Uniprot Entry NameSEM4C_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168758
    Target ClassificationN/A

    The target: SEMA4C, gene name: SEMA4C, also named as M-SEMA-F, SEMACL1, SEMAF, SEMAI. Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in muscle cell differentiation and positive regulation of stress-activated MAPK cascade. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.