Anti-SEMA5B monoclonal antibody

Pre-made anti-SEMA5B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SEMA5B/SEMA5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1607-Ab-1/ GM-Tg-hg-IP1607-Ab-2Anti-Human SEMA5B monoclonal antibodyHuman
GM-Tg-rg-IP1607-Ab-1/ GM-Tg-rg-IP1607-Ab-2Anti-Rat SEMA5B monoclonal antibodyRat
GM-Tg-mg-IP1607-Ab-1/ GM-Tg-mg-IP1607-Ab-2Anti-Mouse SEMA5B monoclonal antibodyMouse
GM-Tg-cynog-IP1607-Ab-1/ GM-Tg-cynog-IP1607-Ab-2Anti-Cynomolgus/ Rhesus macaque SEMA5B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1607-Ab-1/ GM-Tg-felg-IP1607-Ab-2Anti-Feline SEMA5B monoclonal antibodyFeline
GM-Tg-cang-IP1607-Ab-1/ GM-Tg-cang-IP1607-Ab-2Anti-Canine SEMA5B monoclonal antibodyCanine
GM-Tg-bovg-IP1607-Ab-1/ GM-Tg-bovg-IP1607-Ab-2Anti-Bovine SEMA5B monoclonal antibodyBovine
GM-Tg-equg-IP1607-Ab-1/ GM-Tg-equg-IP1607-Ab-2Anti-Equine SEMA5B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1607-Ab-1/ GM-Tg-hg-IP1607-Ab-2; GM-Tg-rg-IP1607-Ab-1/ GM-Tg-rg-IP1607-Ab-2;
GM-Tg-mg-IP1607-Ab-1/ GM-Tg-mg-IP1607-Ab-2; GM-Tg-cynog-IP1607-Ab-1/ GM-Tg-cynog-IP1607-Ab-2;
GM-Tg-felg-IP1607-Ab-1/ GM-Tg-felg-IP1607-Ab-2; GM-Tg-cang-IP1607-Ab-1/ GM-Tg-cang-IP1607-Ab-2;
GM-Tg-bovg-IP1607-Ab-1/ GM-Tg-bovg-IP1607-Ab-2; GM-Tg-equg-IP1607-Ab-1/ GM-Tg-equg-IP1607-Ab-2
Products NameAnti-SEMA5B monoclonal antibody
Formatmab
Target NameSEMA5B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SEMA5B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1607-Ag-1Recombinant multi-species SEM5B/ SEMA5B/ SEMAG protein


    Target information

    Target IDGM-IP1607
    Target NameSEMA5B
    Gene ID54437,20357,303901,715682,100687386,101092390,784494,100070536
    Gene Symbol and SynonymsmKIAA1445,SEMA5B,SEMAG,SemG
    Uniprot AccessionQ9P283
    Uniprot Entry NameSEM5B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000082684
    Target ClassificationN/A

    The target: SEMA5B, gene name: SEMA5B, also named as SEMAG, SemG. This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.