Anti-SERF1B monoclonal antibody
Pre-made anti-SERF1B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1611-Ab-1/ GM-Tg-hg-IP1611-Ab-2 | Anti-Human SERF1B monoclonal antibody | Human |
GM-Tg-rg-IP1611-Ab-1/ GM-Tg-rg-IP1611-Ab-2 | Anti-Rat SERF1B monoclonal antibody | Rat |
GM-Tg-mg-IP1611-Ab-1/ GM-Tg-mg-IP1611-Ab-2 | Anti-Mouse SERF1B monoclonal antibody | Mouse |
GM-Tg-cynog-IP1611-Ab-1/ GM-Tg-cynog-IP1611-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SERF1B monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1611-Ab-1/ GM-Tg-felg-IP1611-Ab-2 | Anti-Feline SERF1B monoclonal antibody | Feline |
GM-Tg-cang-IP1611-Ab-1/ GM-Tg-cang-IP1611-Ab-2 | Anti-Canine SERF1B monoclonal antibody | Canine |
GM-Tg-bovg-IP1611-Ab-1/ GM-Tg-bovg-IP1611-Ab-2 | Anti-Bovine SERF1B monoclonal antibody | Bovine |
GM-Tg-equg-IP1611-Ab-1/ GM-Tg-equg-IP1611-Ab-2 | Anti-Equine SERF1B monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP1611-Ab-1/ GM-Tg-hg-IP1611-Ab-2; GM-Tg-rg-IP1611-Ab-1/ GM-Tg-rg-IP1611-Ab-2; GM-Tg-mg-IP1611-Ab-1/ GM-Tg-mg-IP1611-Ab-2; GM-Tg-cynog-IP1611-Ab-1/ GM-Tg-cynog-IP1611-Ab-2; GM-Tg-felg-IP1611-Ab-1/ GM-Tg-felg-IP1611-Ab-2; GM-Tg-cang-IP1611-Ab-1/ GM-Tg-cang-IP1611-Ab-2; GM-Tg-bovg-IP1611-Ab-1/ GM-Tg-bovg-IP1611-Ab-2; GM-Tg-equg-IP1611-Ab-1/ GM-Tg-equg-IP1611-Ab-2 |
Products Name | Anti-SERF1B monoclonal antibody |
Format | mab |
Target Name | SERF1B |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-SERF1B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP1611-Ag-1 | Recombinant multi-species SERF1B/ FAM2B/ H4F5C protein |
Target information
Target ID | GM-IP1611 |
Target Name | SERF1B |
Gene ID | 728492 |
Gene Symbol and Synonyms | FAM2B,h4F5,H4F5C,SERF1B |
Uniprot Accession | N/A |
Uniprot Entry Name | |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000205572 |
Target Classification | N/A |
The target: SERF1B, gene name: SERF1B, also named as FAM2B, H4F5C, h4F5. This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is the centromeric copy which is identical to the telomeric copy. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene. The gene encodes a protein of unknown function which bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.