Anti-SERINC2 monoclonal antibody

Pre-made anti-SERINC2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SERINC2/SERINC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1612-Ab-1/ GM-Tg-hg-IP1612-Ab-2Anti-Human SERINC2 monoclonal antibodyHuman
GM-Tg-rg-IP1612-Ab-1/ GM-Tg-rg-IP1612-Ab-2Anti-Rat SERINC2 monoclonal antibodyRat
GM-Tg-mg-IP1612-Ab-1/ GM-Tg-mg-IP1612-Ab-2Anti-Mouse SERINC2 monoclonal antibodyMouse
GM-Tg-cynog-IP1612-Ab-1/ GM-Tg-cynog-IP1612-Ab-2Anti-Cynomolgus/ Rhesus macaque SERINC2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1612-Ab-1/ GM-Tg-felg-IP1612-Ab-2Anti-Feline SERINC2 monoclonal antibodyFeline
GM-Tg-cang-IP1612-Ab-1/ GM-Tg-cang-IP1612-Ab-2Anti-Canine SERINC2 monoclonal antibodyCanine
GM-Tg-bovg-IP1612-Ab-1/ GM-Tg-bovg-IP1612-Ab-2Anti-Bovine SERINC2 monoclonal antibodyBovine
GM-Tg-equg-IP1612-Ab-1/ GM-Tg-equg-IP1612-Ab-2Anti-Equine SERINC2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1612-Ab-1/ GM-Tg-hg-IP1612-Ab-2; GM-Tg-rg-IP1612-Ab-1/ GM-Tg-rg-IP1612-Ab-2;
GM-Tg-mg-IP1612-Ab-1/ GM-Tg-mg-IP1612-Ab-2; GM-Tg-cynog-IP1612-Ab-1/ GM-Tg-cynog-IP1612-Ab-2;
GM-Tg-felg-IP1612-Ab-1/ GM-Tg-felg-IP1612-Ab-2; GM-Tg-cang-IP1612-Ab-1/ GM-Tg-cang-IP1612-Ab-2;
GM-Tg-bovg-IP1612-Ab-1/ GM-Tg-bovg-IP1612-Ab-2; GM-Tg-equg-IP1612-Ab-1/ GM-Tg-equg-IP1612-Ab-2
Products NameAnti-SERINC2 monoclonal antibody
Formatmab
Target NameSERINC2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SERINC2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1612-Ag-1Recombinant multi-species SERC2/ SERINC2/ FKSG84 protein
    ORF Viral VectorpGMLPm005110mouse Serinc2 Lentivirus plasmid
    ORF Viral VectorvGMLPm005110mouse Serinc2 Lentivirus particle


    Target information

    Target IDGM-IP1612
    Target NameSERINC2
    Gene ID347735,230779,313057,705303,100855498,101094277,513593,100070470
    Gene Symbol and Synonyms2310004K20Rik,FKSG84,PRO0899,SERINC2,TDE2,TDE2L
    Uniprot AccessionQ96SA4,Q58CW5
    Uniprot Entry NameSERC2_HUMAN,SERC2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000168528
    Target ClassificationN/A

    The target: SERINC2, gene name: SERINC2, also named as FKSG84, PRO0899, TDE2, TDE2L. Predicted to be involved in several processes, including phosphatidylserine metabolic process; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity; and positive regulation of serine C-palmitoyltransferase activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.