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Anti-SHISA2 monoclonal antibody
Pre-made anti-SHISA2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SHISA2/SHISA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1632-Ab-1/ GM-Tg-hg-IP1632-Ab-2 | Anti-Human SHISA2 monoclonal antibody | Human |
| GM-Tg-rg-IP1632-Ab-1/ GM-Tg-rg-IP1632-Ab-2 | Anti-Rat SHISA2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1632-Ab-1/ GM-Tg-mg-IP1632-Ab-2 | Anti-Mouse SHISA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1632-Ab-1/ GM-Tg-cynog-IP1632-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SHISA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1632-Ab-1/ GM-Tg-felg-IP1632-Ab-2 | Anti-Feline SHISA2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1632-Ab-1/ GM-Tg-cang-IP1632-Ab-2 | Anti-Canine SHISA2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1632-Ab-1/ GM-Tg-bovg-IP1632-Ab-2 | Anti-Bovine SHISA2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1632-Ab-1/ GM-Tg-equg-IP1632-Ab-2 | Anti-Equine SHISA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1632-Ab-1/ GM-Tg-hg-IP1632-Ab-2; GM-Tg-rg-IP1632-Ab-1/ GM-Tg-rg-IP1632-Ab-2; GM-Tg-mg-IP1632-Ab-1/ GM-Tg-mg-IP1632-Ab-2; GM-Tg-cynog-IP1632-Ab-1/ GM-Tg-cynog-IP1632-Ab-2; GM-Tg-felg-IP1632-Ab-1/ GM-Tg-felg-IP1632-Ab-2; GM-Tg-cang-IP1632-Ab-1/ GM-Tg-cang-IP1632-Ab-2; GM-Tg-bovg-IP1632-Ab-1/ GM-Tg-bovg-IP1632-Ab-2; GM-Tg-equg-IP1632-Ab-1/ GM-Tg-equg-IP1632-Ab-2 |
| Products Name | Anti-SHISA2 monoclonal antibody |
| Format | mab |
| Target Name | SHISA2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SHISA2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1632-Ag-1 | Recombinant multi-species SHSA2/ SHISA2/ C13orf13 protein |
| ORF Viral Vector | vGMLP004981 | human SHISA2 Lentivirus particle |
| ORF Viral Vector | pGMLP004981 | human SHISA2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001312 | mouse Shisa2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001312 | mouse Shisa2 Lentivirus particle |
Target information
| Target ID | GM-IP1632 |
| Target Name | SHISA2 |
| Gene ID | 387914,219134,498528,709404,119865914,101096529,617336,100050662 |
| Gene Symbol and Synonyms | 9430059P22Rik,bA398O19.2,C13orf13,hShisa,MAd2,mShisa,PRO28631,RGD1561256,shisa,SHISA2,™EM46,WGAR9166 |
| Uniprot Accession | Q6UWI4,A6QPA0 |
| Uniprot Entry Name | SHSA2_HUMAN,SHSA2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000180730 |
| Target Classification | N/A |
The target: SHISA2, gene name: SHISA2, also named as C13orf13, PRO28631, ™EM46, WGAR9166, bA398O19.2, hShisa. Predicted to be involved in negative regulation of Wnt signaling pathway and negative regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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