Anti-SHISA5 monoclonal antibody

Pre-made anti-SHISA5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SHISA5/SHISA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1635-Ab-1/ GM-Tg-hg-IP1635-Ab-2Anti-Human SHISA5 monoclonal antibodyHuman
GM-Tg-rg-IP1635-Ab-1/ GM-Tg-rg-IP1635-Ab-2Anti-Rat SHISA5 monoclonal antibodyRat
GM-Tg-mg-IP1635-Ab-1/ GM-Tg-mg-IP1635-Ab-2Anti-Mouse SHISA5 monoclonal antibodyMouse
GM-Tg-cynog-IP1635-Ab-1/ GM-Tg-cynog-IP1635-Ab-2Anti-Cynomolgus/ Rhesus macaque SHISA5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1635-Ab-1/ GM-Tg-felg-IP1635-Ab-2Anti-Feline SHISA5 monoclonal antibodyFeline
GM-Tg-cang-IP1635-Ab-1/ GM-Tg-cang-IP1635-Ab-2Anti-Canine SHISA5 monoclonal antibodyCanine
GM-Tg-bovg-IP1635-Ab-1/ GM-Tg-bovg-IP1635-Ab-2Anti-Bovine SHISA5 monoclonal antibodyBovine
GM-Tg-equg-IP1635-Ab-1/ GM-Tg-equg-IP1635-Ab-2Anti-Equine SHISA5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1635-Ab-1/ GM-Tg-hg-IP1635-Ab-2; GM-Tg-rg-IP1635-Ab-1/ GM-Tg-rg-IP1635-Ab-2;
GM-Tg-mg-IP1635-Ab-1/ GM-Tg-mg-IP1635-Ab-2; GM-Tg-cynog-IP1635-Ab-1/ GM-Tg-cynog-IP1635-Ab-2;
GM-Tg-felg-IP1635-Ab-1/ GM-Tg-felg-IP1635-Ab-2; GM-Tg-cang-IP1635-Ab-1/ GM-Tg-cang-IP1635-Ab-2;
GM-Tg-bovg-IP1635-Ab-1/ GM-Tg-bovg-IP1635-Ab-2; GM-Tg-equg-IP1635-Ab-1/ GM-Tg-equg-IP1635-Ab-2
Products NameAnti-SHISA5 monoclonal antibody
Formatmab
Target NameSHISA5
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SHISA5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1635-Ag-1Recombinant multi-species SHSA5/ SHISA5/ SCOTIN protein


    Target information

    Target IDGM-IP1635
    Target NameSHISA5
    Gene ID51246,66940,301013,709615,609054,101099189,616861,100063734
    Gene Symbol and Synonyms2310008D10Rik,6430628I05Rik,mShisa5,SCOTIN,SHISA5
    Uniprot AccessionQ8N114,Q5XIH2,Q3T0A9
    Uniprot Entry NameSHSA5_HUMAN,SHSA5_RAT,SHSA5_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164054
    Target ClassificationN/A

    The target: SHISA5, gene name: SHISA5, also named as SCOTIN. This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. Related pseudogenes of this gene are found on chromosome X. [provided by RefSeq, Apr 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.