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Anti-SLC17A4 monoclonal antibody
Pre-made anti-SLC17A4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC17A4/SLC17A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1653-Ab-1/ GM-Tg-hg-IP1653-Ab-2 | Anti-Human SLC17A4 monoclonal antibody | Human |
| GM-Tg-rg-IP1653-Ab-1/ GM-Tg-rg-IP1653-Ab-2 | Anti-Rat SLC17A4 monoclonal antibody | Rat |
| GM-Tg-mg-IP1653-Ab-1/ GM-Tg-mg-IP1653-Ab-2 | Anti-Mouse SLC17A4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1653-Ab-1/ GM-Tg-cynog-IP1653-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC17A4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1653-Ab-1/ GM-Tg-felg-IP1653-Ab-2 | Anti-Feline SLC17A4 monoclonal antibody | Feline |
| GM-Tg-cang-IP1653-Ab-1/ GM-Tg-cang-IP1653-Ab-2 | Anti-Canine SLC17A4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1653-Ab-1/ GM-Tg-bovg-IP1653-Ab-2 | Anti-Bovine SLC17A4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1653-Ab-1/ GM-Tg-equg-IP1653-Ab-2 | Anti-Equine SLC17A4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1653-Ab-1/ GM-Tg-hg-IP1653-Ab-2; GM-Tg-rg-IP1653-Ab-1/ GM-Tg-rg-IP1653-Ab-2; GM-Tg-mg-IP1653-Ab-1/ GM-Tg-mg-IP1653-Ab-2; GM-Tg-cynog-IP1653-Ab-1/ GM-Tg-cynog-IP1653-Ab-2; GM-Tg-felg-IP1653-Ab-1/ GM-Tg-felg-IP1653-Ab-2; GM-Tg-cang-IP1653-Ab-1/ GM-Tg-cang-IP1653-Ab-2; GM-Tg-bovg-IP1653-Ab-1/ GM-Tg-bovg-IP1653-Ab-2; GM-Tg-equg-IP1653-Ab-1/ GM-Tg-equg-IP1653-Ab-2 |
| Products Name | Anti-SLC17A4 monoclonal antibody |
| Format | mab |
| Target Name | SLC17A4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC17A4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1653-Ag-1 | Recombinant multi-species S17A4/ SLC17A4/ KAIA2138 protein |
Target information
| Target ID | GM-IP1653 |
| Target Name | SLC17A4 |
| Gene ID | 10050,319848,679784,694213,100688596,101085718,512725,100052756 |
| Gene Symbol and Synonyms | 9130214H05Rik,KAIA2138,SLC17A4 |
| Uniprot Accession | Q9Y2C5 |
| Uniprot Entry Name | S17A4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000146039 |
| Target Classification | N/A |
The target: SLC17A4, gene name: SLC17A4, also named as KAIA2138. Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]).[supplied by OMIM, Feb 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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