Anti-SLC17A6 monoclonal antibody

Pre-made anti-SLC17A6 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SLC17A6/SLC17A6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1654-Ab-1/ GM-Tg-hg-IP1654-Ab-2Anti-Human SLC17A6 monoclonal antibodyHuman
GM-Tg-rg-IP1654-Ab-1/ GM-Tg-rg-IP1654-Ab-2Anti-Rat SLC17A6 monoclonal antibodyRat
GM-Tg-mg-IP1654-Ab-1/ GM-Tg-mg-IP1654-Ab-2Anti-Mouse SLC17A6 monoclonal antibodyMouse
GM-Tg-cynog-IP1654-Ab-1/ GM-Tg-cynog-IP1654-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC17A6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1654-Ab-1/ GM-Tg-felg-IP1654-Ab-2Anti-Feline SLC17A6 monoclonal antibodyFeline
GM-Tg-cang-IP1654-Ab-1/ GM-Tg-cang-IP1654-Ab-2Anti-Canine SLC17A6 monoclonal antibodyCanine
GM-Tg-bovg-IP1654-Ab-1/ GM-Tg-bovg-IP1654-Ab-2Anti-Bovine SLC17A6 monoclonal antibodyBovine
GM-Tg-equg-IP1654-Ab-1/ GM-Tg-equg-IP1654-Ab-2Anti-Equine SLC17A6 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1654-Ab-1/ GM-Tg-hg-IP1654-Ab-2; GM-Tg-rg-IP1654-Ab-1/ GM-Tg-rg-IP1654-Ab-2;
GM-Tg-mg-IP1654-Ab-1/ GM-Tg-mg-IP1654-Ab-2; GM-Tg-cynog-IP1654-Ab-1/ GM-Tg-cynog-IP1654-Ab-2;
GM-Tg-felg-IP1654-Ab-1/ GM-Tg-felg-IP1654-Ab-2; GM-Tg-cang-IP1654-Ab-1/ GM-Tg-cang-IP1654-Ab-2;
GM-Tg-bovg-IP1654-Ab-1/ GM-Tg-bovg-IP1654-Ab-2; GM-Tg-equg-IP1654-Ab-1/ GM-Tg-equg-IP1654-Ab-2
Products NameAnti-SLC17A6 monoclonal antibody
Formatmab
Target NameSLC17A6
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SLC17A6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1654-Ag-1Recombinant multi-species VGLU2/ SLC17A6/ DNPI protein
    ORF Viral VectorpGMLPm003004mouse Slc17a6 Lentivirus plasmid
    ORF Viral VectorvGMLPm003004mouse Slc17a6 Lentivirus particle


    Target information

    Target IDGM-IP1654
    Target NameSLC17A6
    Gene ID57084,140919,84487,100425977,100316859,101098576,100125225,100057463
    Gene Symbol and Synonyms2900073D12Rik,DNPI,SLC17A6,VGLUT2
    Uniprot AccessionQ9P2U8,Q9JI12,A6QLI1
    Uniprot Entry NameVGLU2_HUMAN,VGLU2_RAT,VGLU2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000091664
    Target ClassificationN/A

    The target: SLC17A6, gene name: SLC17A6, also named as DNPI, VGLUT2. Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in neurotransmitter loading into synaptic vesicle. Predicted to be located in synaptic vesicle. Predicted to be active in excitatory synapse. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.