Anti-SLC25A22 monoclonal antibody
Pre-made anti-SLC25A22 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1671-Ab-1/ GM-Tg-hg-IP1671-Ab-2 | Anti-Human SLC25A22 monoclonal antibody | Human |
GM-Tg-rg-IP1671-Ab-1/ GM-Tg-rg-IP1671-Ab-2 | Anti-Rat SLC25A22 monoclonal antibody | Rat |
GM-Tg-mg-IP1671-Ab-1/ GM-Tg-mg-IP1671-Ab-2 | Anti-Mouse SLC25A22 monoclonal antibody | Mouse |
GM-Tg-cynog-IP1671-Ab-1/ GM-Tg-cynog-IP1671-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC25A22 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1671-Ab-1/ GM-Tg-felg-IP1671-Ab-2 | Anti-Feline SLC25A22 monoclonal antibody | Feline |
GM-Tg-cang-IP1671-Ab-1/ GM-Tg-cang-IP1671-Ab-2 | Anti-Canine SLC25A22 monoclonal antibody | Canine |
GM-Tg-bovg-IP1671-Ab-1/ GM-Tg-bovg-IP1671-Ab-2 | Anti-Bovine SLC25A22 monoclonal antibody | Bovine |
GM-Tg-equg-IP1671-Ab-1/ GM-Tg-equg-IP1671-Ab-2 | Anti-Equine SLC25A22 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP1671-Ab-1/ GM-Tg-hg-IP1671-Ab-2; GM-Tg-rg-IP1671-Ab-1/ GM-Tg-rg-IP1671-Ab-2; GM-Tg-mg-IP1671-Ab-1/ GM-Tg-mg-IP1671-Ab-2; GM-Tg-cynog-IP1671-Ab-1/ GM-Tg-cynog-IP1671-Ab-2; GM-Tg-felg-IP1671-Ab-1/ GM-Tg-felg-IP1671-Ab-2; GM-Tg-cang-IP1671-Ab-1/ GM-Tg-cang-IP1671-Ab-2; GM-Tg-bovg-IP1671-Ab-1/ GM-Tg-bovg-IP1671-Ab-2; GM-Tg-equg-IP1671-Ab-1/ GM-Tg-equg-IP1671-Ab-2 |
Products Name | Anti-SLC25A22 monoclonal antibody |
Format | mab |
Target Name | SLC25A22 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-SLC25A22 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP1671-Ag-1 | Recombinant multi-species GHC1/ SLC25A22/ EIEE3 protein |
ORF Viral Vector | vGMLP004059 | human SLC25A22 Lentivirus particle |
ORF Viral Vector | pGMLP004059 | human SLC25A22 Lentivirus plasmid |
ORF Viral Vector | pGMLPm004133 | mouse Slc25a22 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004133 | mouse Slc25a22 Lentivirus particle |
Target information
Target ID | GM-IP1671 |
Target Name | SLC25A22 |
Gene ID | 79751,68267,309111,700463,119864201,101098990,504371,100147341 |
Gene Symbol and Synonyms | 1300006L01Rik,DEE3,EIEE3,GC-1,GC1,NET44,RGD1307826,SLC25A22 |
Uniprot Accession | Q9H936,A0A0G2K5L2,Q08DK4 |
Uniprot Entry Name | GHC1_HUMAN,A0A0G2K5L2_RAT,GHC1_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000177542 |
Target Classification | N/A |
The target: SLC25A22, gene name: SLC25A22, also named as EIEE3, GC-1, GC1, NET44. This gene encodes a mitochondrial glutamate carrier. Mutations in this gene are associated with early infantile epileptic encephalopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jul 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.