Anti-SLC25A46 monoclonal antibody

Pre-made anti-SLC25A46 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SLC25A46/SLC25A46 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1685-Ab-1/ GM-Tg-hg-IP1685-Ab-2Anti-Human SLC25A46 monoclonal antibodyHuman
GM-Tg-rg-IP1685-Ab-1/ GM-Tg-rg-IP1685-Ab-2Anti-Rat SLC25A46 monoclonal antibodyRat
GM-Tg-mg-IP1685-Ab-1/ GM-Tg-mg-IP1685-Ab-2Anti-Mouse SLC25A46 monoclonal antibodyMouse
GM-Tg-cynog-IP1685-Ab-1/ GM-Tg-cynog-IP1685-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC25A46 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1685-Ab-1/ GM-Tg-felg-IP1685-Ab-2Anti-Feline SLC25A46 monoclonal antibodyFeline
GM-Tg-cang-IP1685-Ab-1/ GM-Tg-cang-IP1685-Ab-2Anti-Canine SLC25A46 monoclonal antibodyCanine
GM-Tg-bovg-IP1685-Ab-1/ GM-Tg-bovg-IP1685-Ab-2Anti-Bovine SLC25A46 monoclonal antibodyBovine
GM-Tg-equg-IP1685-Ab-1/ GM-Tg-equg-IP1685-Ab-2Anti-Equine SLC25A46 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1685-Ab-1/ GM-Tg-hg-IP1685-Ab-2; GM-Tg-rg-IP1685-Ab-1/ GM-Tg-rg-IP1685-Ab-2;
GM-Tg-mg-IP1685-Ab-1/ GM-Tg-mg-IP1685-Ab-2; GM-Tg-cynog-IP1685-Ab-1/ GM-Tg-cynog-IP1685-Ab-2;
GM-Tg-felg-IP1685-Ab-1/ GM-Tg-felg-IP1685-Ab-2; GM-Tg-cang-IP1685-Ab-1/ GM-Tg-cang-IP1685-Ab-2;
GM-Tg-bovg-IP1685-Ab-1/ GM-Tg-bovg-IP1685-Ab-2; GM-Tg-equg-IP1685-Ab-1/ GM-Tg-equg-IP1685-Ab-2
Products NameAnti-SLC25A46 monoclonal antibody
Formatmab
Target NameSLC25A46
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SLC25A46 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1685-Ag-1Recombinant multi-species S2546/ SLC25A46/ HMSN6B protein


    Target information

    Target IDGM-IP1685
    Target NameSLC25A46
    Gene ID91137,67453,291709,705968,488876,101095153,531725,100064546
    Gene Symbol and Synonyms1200007B05Rik,HMSN6B,PCH1E,RGD1305072,SLC25A46
    Uniprot AccessionQ96AG3,Q5EB62
    Uniprot Entry NameS2546_HUMAN,S2546_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164209
    Target ClassificationN/A

    The target: SLC25A46, gene name: SLC25A46, also named as HMSN6B. This gene encodes a mitochondrial solute carrier protein family member. It functions in promoting mitochondrial fission, and prevents the formation of hyperfilamentous mitochondria. Mutation of this gene results in neuropathy and optic atrophy. [provided by RefSeq, Aug 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.