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Anti-SLC35D2 monoclonal antibody
Pre-made anti-SLC35D2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC35D2/SLC35D2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1712-Ab-1/ GM-Tg-hg-IP1712-Ab-2 | Anti-Human SLC35D2 monoclonal antibody | Human |
| GM-Tg-rg-IP1712-Ab-1/ GM-Tg-rg-IP1712-Ab-2 | Anti-Rat SLC35D2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1712-Ab-1/ GM-Tg-mg-IP1712-Ab-2 | Anti-Mouse SLC35D2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1712-Ab-1/ GM-Tg-cynog-IP1712-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC35D2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1712-Ab-1/ GM-Tg-felg-IP1712-Ab-2 | Anti-Feline SLC35D2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1712-Ab-1/ GM-Tg-cang-IP1712-Ab-2 | Anti-Canine SLC35D2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1712-Ab-1/ GM-Tg-bovg-IP1712-Ab-2 | Anti-Bovine SLC35D2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1712-Ab-1/ GM-Tg-equg-IP1712-Ab-2 | Anti-Equine SLC35D2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1712-Ab-1/ GM-Tg-hg-IP1712-Ab-2; GM-Tg-rg-IP1712-Ab-1/ GM-Tg-rg-IP1712-Ab-2; GM-Tg-mg-IP1712-Ab-1/ GM-Tg-mg-IP1712-Ab-2; GM-Tg-cynog-IP1712-Ab-1/ GM-Tg-cynog-IP1712-Ab-2; GM-Tg-felg-IP1712-Ab-1/ GM-Tg-felg-IP1712-Ab-2; GM-Tg-cang-IP1712-Ab-1/ GM-Tg-cang-IP1712-Ab-2; GM-Tg-bovg-IP1712-Ab-1/ GM-Tg-bovg-IP1712-Ab-2; GM-Tg-equg-IP1712-Ab-1/ GM-Tg-equg-IP1712-Ab-2 |
| Products Name | Anti-SLC35D2 monoclonal antibody |
| Format | mab |
| Target Name | SLC35D2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC35D2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1712-Ag-1 | Recombinant multi-species S35D2/ SLC35D2/ HFRC1 protein |
Target information
| Target ID | GM-IP1712 |
| Target Name | SLC35D2 |
| Gene ID | 11046,70484,290959,719257,100856233,101089404,617113,100062655 |
| Gene Symbol and Synonyms | 5730408I21Rik,hfrc,HFRC1,mUGTrel8,SLC35D2,SQV7L,UGTrel8 |
| Uniprot Accession | Q76EJ3 |
| Uniprot Entry Name | S35D2_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130958 |
| Target Classification | N/A |
The target: SLC35D2, gene name: SLC35D2, also named as HFRC1, SQV7L, UGTrel8, hfrc. Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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